Calcium ions protect cell-substratum adhesion receptors against proteolysis. Evidence from immunoabsorption and electroblotting studies

Nancy Oppenheimer-Marks, Frederick Grinnell

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Abstract

An antibody preparation against BHK cell wheat germ agglutinin receptors (anti-WGA-R), which inhibits fibronectin-mediated cell adhesion, was characterized by immunoabsorption and electroblotting experiments. The results indicated that a 48 kD cell surface WGA-R receptor is protected from proteolysis by Ca2+ ions and is important in fibronectin-mediated cell adhesion.

Original languageEnglish (US)
Pages (from-to)467-475
Number of pages9
JournalExperimental Cell Research
Volume152
Issue number2
DOIs
Publication statusPublished - 1984

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ASJC Scopus subject areas

  • Cell Biology

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