Cardiac myxoma causing acute ischemic stroke in a pediatric patient and a review of literature

Jennifer Fuchs, David Leszczyszyn, Don Mathew

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background Ischemic stroke in the pediatric population is a rare occurrence, and its possible causes span a wide differential that includes atrial myxomas. Myxomas are friable cardiac tumors that produce "showers" of emboli resulting in transient neurological deficits, cutaneous eruptions, and ophthalmologic deficits. Patient We present an 11-year-old boy with a months-long history of an intermittent spotted "rash" who presented with acute ischemic stroke caused by a left atrial myxoma. We also review clinical features in all 16 other cases of cardiac myxoma causing pediatric stroke reported in the literature. Results Our case, along with the review of the literature, highlights the fact that myxomas often initially present as stroke with acute hemiplegia and transient cutaneous eruptions due to fragmentation of the tumor. Conclusions Cardiac myxoma should be considered in any child presenting with ischemic stroke, and transient skin findings may provide an important diagnostic clue prior to onset of neurological symptoms.

Original languageEnglish (US)
Pages (from-to)525-529
Number of pages5
JournalPediatric Neurology
Volume50
Issue number5
DOIs
StatePublished - Jan 1 2014

Fingerprint

Myxoma
Stroke
Pediatrics
Skin
Heart Neoplasms
Hemiplegia
Exanthema
Embolism
Population
Neoplasms

Keywords

  • acute hemiplegia
  • cardiac myxoma
  • children
  • evanescent rash
  • retinal artery occlusion
  • stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology
  • Medicine(all)

Cite this

Cardiac myxoma causing acute ischemic stroke in a pediatric patient and a review of literature. / Fuchs, Jennifer; Leszczyszyn, David; Mathew, Don.

In: Pediatric Neurology, Vol. 50, No. 5, 01.01.2014, p. 525-529.

Research output: Contribution to journalArticle

Fuchs, Jennifer ; Leszczyszyn, David ; Mathew, Don. / Cardiac myxoma causing acute ischemic stroke in a pediatric patient and a review of literature. In: Pediatric Neurology. 2014 ; Vol. 50, No. 5. pp. 525-529.
@article{622fbb5869004fde9e0e8cdeb6825b59,
title = "Cardiac myxoma causing acute ischemic stroke in a pediatric patient and a review of literature",
abstract = "Background Ischemic stroke in the pediatric population is a rare occurrence, and its possible causes span a wide differential that includes atrial myxomas. Myxomas are friable cardiac tumors that produce {"}showers{"} of emboli resulting in transient neurological deficits, cutaneous eruptions, and ophthalmologic deficits. Patient We present an 11-year-old boy with a months-long history of an intermittent spotted {"}rash{"} who presented with acute ischemic stroke caused by a left atrial myxoma. We also review clinical features in all 16 other cases of cardiac myxoma causing pediatric stroke reported in the literature. Results Our case, along with the review of the literature, highlights the fact that myxomas often initially present as stroke with acute hemiplegia and transient cutaneous eruptions due to fragmentation of the tumor. Conclusions Cardiac myxoma should be considered in any child presenting with ischemic stroke, and transient skin findings may provide an important diagnostic clue prior to onset of neurological symptoms.",
keywords = "acute hemiplegia, cardiac myxoma, children, evanescent rash, retinal artery occlusion, stroke",
author = "Jennifer Fuchs and David Leszczyszyn and Don Mathew",
year = "2014",
month = "1",
day = "1",
doi = "10.1016/j.pediatrneurol.2014.01.011",
language = "English (US)",
volume = "50",
pages = "525--529",
journal = "Pediatric Neurology",
issn = "0887-8994",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Cardiac myxoma causing acute ischemic stroke in a pediatric patient and a review of literature

AU - Fuchs, Jennifer

AU - Leszczyszyn, David

AU - Mathew, Don

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Background Ischemic stroke in the pediatric population is a rare occurrence, and its possible causes span a wide differential that includes atrial myxomas. Myxomas are friable cardiac tumors that produce "showers" of emboli resulting in transient neurological deficits, cutaneous eruptions, and ophthalmologic deficits. Patient We present an 11-year-old boy with a months-long history of an intermittent spotted "rash" who presented with acute ischemic stroke caused by a left atrial myxoma. We also review clinical features in all 16 other cases of cardiac myxoma causing pediatric stroke reported in the literature. Results Our case, along with the review of the literature, highlights the fact that myxomas often initially present as stroke with acute hemiplegia and transient cutaneous eruptions due to fragmentation of the tumor. Conclusions Cardiac myxoma should be considered in any child presenting with ischemic stroke, and transient skin findings may provide an important diagnostic clue prior to onset of neurological symptoms.

AB - Background Ischemic stroke in the pediatric population is a rare occurrence, and its possible causes span a wide differential that includes atrial myxomas. Myxomas are friable cardiac tumors that produce "showers" of emboli resulting in transient neurological deficits, cutaneous eruptions, and ophthalmologic deficits. Patient We present an 11-year-old boy with a months-long history of an intermittent spotted "rash" who presented with acute ischemic stroke caused by a left atrial myxoma. We also review clinical features in all 16 other cases of cardiac myxoma causing pediatric stroke reported in the literature. Results Our case, along with the review of the literature, highlights the fact that myxomas often initially present as stroke with acute hemiplegia and transient cutaneous eruptions due to fragmentation of the tumor. Conclusions Cardiac myxoma should be considered in any child presenting with ischemic stroke, and transient skin findings may provide an important diagnostic clue prior to onset of neurological symptoms.

KW - acute hemiplegia

KW - cardiac myxoma

KW - children

KW - evanescent rash

KW - retinal artery occlusion

KW - stroke

UR - http://www.scopus.com/inward/record.url?scp=84921425047&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84921425047&partnerID=8YFLogxK

U2 - 10.1016/j.pediatrneurol.2014.01.011

DO - 10.1016/j.pediatrneurol.2014.01.011

M3 - Article

C2 - 24731846

AN - SCOPUS:84921425047

VL - 50

SP - 525

EP - 529

JO - Pediatric Neurology

JF - Pediatric Neurology

SN - 0887-8994

IS - 5

ER -