Cardiac transplantation for pediatric giant cell myocarditis

Bibhuti B. Das, Michael Recto, Christopher Johnsrude, Lisa Klein, Karen Orman, Lawrence Shoemaker, Michael Mitchell, Erle H. Austin

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.

Original languageEnglish (US)
Pages (from-to)474-478
Number of pages5
JournalJournal of Heart and Lung Transplantation
Volume25
Issue number4
DOIs
StatePublished - Apr 1 2006

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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    Das, B. B., Recto, M., Johnsrude, C., Klein, L., Orman, K., Shoemaker, L., Mitchell, M., & Austin, E. H. (2006). Cardiac transplantation for pediatric giant cell myocarditis. Journal of Heart and Lung Transplantation, 25(4), 474-478. https://doi.org/10.1016/j.healun.2005.11.444