Cardiac transplantation for pediatric giant cell myocarditis

Bibhuti B. Das, Michael Recto, Christopher Johnsrude, Lisa Klein, Karen Orman, Lawrence Shoemaker, Michael Mitchell, Erle H. Austin

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.

Original languageEnglish (US)
Pages (from-to)474-478
Number of pages5
JournalJournal of Heart and Lung Transplantation
Volume25
Issue number4
DOIs
StatePublished - Apr 2006

Fingerprint

Myocarditis
Giant Cells
Heart Transplantation
Pediatrics
Extracorporeal Membrane Oxygenation
Immunosuppressive Agents
Ventricular Tachycardia
Autoimmune Diseases
Epidemiology
Hemodynamics
Demography
Transplants

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Transplantation

Cite this

Das, B. B., Recto, M., Johnsrude, C., Klein, L., Orman, K., Shoemaker, L., ... Austin, E. H. (2006). Cardiac transplantation for pediatric giant cell myocarditis. Journal of Heart and Lung Transplantation, 25(4), 474-478. https://doi.org/10.1016/j.healun.2005.11.444

Cardiac transplantation for pediatric giant cell myocarditis. / Das, Bibhuti B.; Recto, Michael; Johnsrude, Christopher; Klein, Lisa; Orman, Karen; Shoemaker, Lawrence; Mitchell, Michael; Austin, Erle H.

In: Journal of Heart and Lung Transplantation, Vol. 25, No. 4, 04.2006, p. 474-478.

Research output: Contribution to journalArticle

Das, BB, Recto, M, Johnsrude, C, Klein, L, Orman, K, Shoemaker, L, Mitchell, M & Austin, EH 2006, 'Cardiac transplantation for pediatric giant cell myocarditis', Journal of Heart and Lung Transplantation, vol. 25, no. 4, pp. 474-478. https://doi.org/10.1016/j.healun.2005.11.444
Das, Bibhuti B. ; Recto, Michael ; Johnsrude, Christopher ; Klein, Lisa ; Orman, Karen ; Shoemaker, Lawrence ; Mitchell, Michael ; Austin, Erle H. / Cardiac transplantation for pediatric giant cell myocarditis. In: Journal of Heart and Lung Transplantation. 2006 ; Vol. 25, No. 4. pp. 474-478.
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