Cell forces meet cell metabolism

Tadamoto Isogai, Jin Suk Park, Gaudenz Danuser

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Epithelial cells form energetically costly cell-cell adhesions in response to mechanical forces. How cells obtain their energy during this event is unclear. Activity of a key regulator of cell metabolism, the AMP-activated protein kinase (AMPK), is now shown to be mechanoresponsive, and thus can bridge adhesion mechanotransduction and energy homeostasis.

Original languageEnglish (US)
Pages (from-to)591-593
Number of pages3
JournalNature Cell Biology
Volume19
Issue number6
DOIs
StatePublished - May 31 2017

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AMP-Activated Protein Kinases
Cell Adhesion
Homeostasis
Epithelial Cells

ASJC Scopus subject areas

  • Cell Biology

Cite this

Cell forces meet cell metabolism. / Isogai, Tadamoto; Park, Jin Suk; Danuser, Gaudenz.

In: Nature Cell Biology, Vol. 19, No. 6, 31.05.2017, p. 591-593.

Research output: Contribution to journalReview article

Isogai, Tadamoto ; Park, Jin Suk ; Danuser, Gaudenz. / Cell forces meet cell metabolism. In: Nature Cell Biology. 2017 ; Vol. 19, No. 6. pp. 591-593.
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