Cerebral activation covaries with movement rate

Gottfried Schlaug, Jerome N. Sanes, Venkatesan Thangaraj, David G. Darby, Lutz Jäncke, Robert R. Edelman, Steven Warach

Research output: Contribution to journalArticle

136 Citations (Scopus)

Abstract

AN important aspect in brain activation studies is the relationship between neuronal activity and measurable indices of function. We applied functional magnetic resonance imaging (fMRI) to investigate blood flow- related MR signal changes in response to different rates of repetitive movements of the index finger. The contralateral precentral gyrus and the posterior frontomesial cortex revealed a significant increase in MR signal over baseline for 1, 2 and 3 Hz finger movements, with a linear effect of rate in the precentral gyrus. Increased firing of neuronal aggregates or recruitment of additional neuronal units within the primary motor cortex necessary for increased output to target neurons and maintaining posture of nearby distal and proximal joints may contribute to the activation pattern.

Original languageEnglish (US)
Pages (from-to)879-883
Number of pages5
JournalNeuroReport
Volume7
Issue number4
StatePublished - 1996

Fingerprint

Frontal Lobe
Fingers
Motor Cortex
Posture
Joints
Magnetic Resonance Imaging
Neurons
Brain

Keywords

  • Cerebral blood flow
  • Functional magnetic resonance imaging
  • Motor control
  • Motor cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Schlaug, G., Sanes, J. N., Thangaraj, V., Darby, D. G., Jäncke, L., Edelman, R. R., & Warach, S. (1996). Cerebral activation covaries with movement rate. NeuroReport, 7(4), 879-883.

Cerebral activation covaries with movement rate. / Schlaug, Gottfried; Sanes, Jerome N.; Thangaraj, Venkatesan; Darby, David G.; Jäncke, Lutz; Edelman, Robert R.; Warach, Steven.

In: NeuroReport, Vol. 7, No. 4, 1996, p. 879-883.

Research output: Contribution to journalArticle

Schlaug, G, Sanes, JN, Thangaraj, V, Darby, DG, Jäncke, L, Edelman, RR & Warach, S 1996, 'Cerebral activation covaries with movement rate', NeuroReport, vol. 7, no. 4, pp. 879-883.
Schlaug G, Sanes JN, Thangaraj V, Darby DG, Jäncke L, Edelman RR et al. Cerebral activation covaries with movement rate. NeuroReport. 1996;7(4):879-883.
Schlaug, Gottfried ; Sanes, Jerome N. ; Thangaraj, Venkatesan ; Darby, David G. ; Jäncke, Lutz ; Edelman, Robert R. ; Warach, Steven. / Cerebral activation covaries with movement rate. In: NeuroReport. 1996 ; Vol. 7, No. 4. pp. 879-883.
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