Cerebral vasculitis in acute post-streptococcal glomerulonephritis

Richard A. Kaplan, David L. Zwick, Stanley Hellerstein, Bradley A. Warady, Uri Alon

Research output: Contribution to journalArticle

20 Scopus citations


Neurological complications in acute post-streptococcal glomerulonephritis (APSGN) have been traditionally attributed to hypertensive encephalopathy. A 9-year-old girl with biopsy-documented APSGN developed seizures at a time she was normotensive and biochemically well balanced. Computed tomography of her brain was consistent with vasculitis, a finding which was also clinically supported by apparent vasculitic involvement of other organ systems. All clinical, laboratory and radiological abnormalities resolved with recovery from the APSGN. We suggest that on rare occasions neurological complications in APSGN may result from involvement of the central nervous system in multiorgan transient vasculitis.

Original languageEnglish (US)
Pages (from-to)194-195
Number of pages2
JournalPediatric Nephrology
Issue number2
StatePublished - Apr 1 1993


  • Computed tomography
  • Electroencephalography
  • Post-streptococcal glomerulonephritis
  • Seizures
  • Vasculitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

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    Kaplan, R. A., Zwick, D. L., Hellerstein, S., Warady, B. A., & Alon, U. (1993). Cerebral vasculitis in acute post-streptococcal glomerulonephritis. Pediatric Nephrology, 7(2), 194-195. https://doi.org/10.1007/BF00864396