Challenging cases in rheumatic pregnancies

Cuoghi Edens, Bruna Costa Rodrigues, Marcela Ignacchiti Lacerda, Flavia Cunha Dos Santos, Guilherme R. De Jesús, Nilson Ramires De Jesús, Roger A. Levy, Cianna Leatherwood, Jess Mandel, Bonnie Bermas

Research output: Contribution to journalArticle

Abstract

This article describes three complicated cases in rheumatology and pregnancy. The first case elucidates the challenges in treating SLE in conjunction with pulmonary arterial hypertension, while the second case features an SLE-affected pregnancy with development of portal hypertension secondary to portal vein thrombosis related to APS. The third case is a pregnant woman with stable SLE who developed thrombotic microangiopathy caused by atypical haemolytic uraemic syndrome, and failed to improve despite multiple measures including biopsy and elective preterm delivery. There are grave and unique challenges for women with autoimmune disease, but adverse outcomes can sometimes be avoided with careful and multidisciplinary medical management. Pre-conception counselling with regard to medications and disease treatment should also include discussion of the advisability of pregnancy, which may be difficult for a patient, but present the best course for optimizing health outcomes.

Original languageEnglish (US)
Pages (from-to)v18-v25
JournalRheumatology (Oxford, England)
Volume57
Issue number5
DOIs
StatePublished - Jul 1 2018

Fingerprint

Pregnancy
Thrombotic Microangiopathies
Rheumatology
Portal Hypertension
Portal Vein
Pulmonary Hypertension
Autoimmune Diseases
Counseling
Pregnant Women
Thrombosis
Biopsy
Health
Therapeutics
Atypical Hemolytic Uremic Syndrome

ASJC Scopus subject areas

  • Rheumatology
  • Pharmacology (medical)

Cite this

Edens, C., Rodrigues, B. C., Lacerda, M. I., Dos Santos, F. C., De Jesús, G. R., De Jesús, N. R., ... Bermas, B. (2018). Challenging cases in rheumatic pregnancies. Rheumatology (Oxford, England), 57(5), v18-v25. https://doi.org/10.1093/rheumatology/key172

Challenging cases in rheumatic pregnancies. / Edens, Cuoghi; Rodrigues, Bruna Costa; Lacerda, Marcela Ignacchiti; Dos Santos, Flavia Cunha; De Jesús, Guilherme R.; De Jesús, Nilson Ramires; Levy, Roger A.; Leatherwood, Cianna; Mandel, Jess; Bermas, Bonnie.

In: Rheumatology (Oxford, England), Vol. 57, No. 5, 01.07.2018, p. v18-v25.

Research output: Contribution to journalArticle

Edens, C, Rodrigues, BC, Lacerda, MI, Dos Santos, FC, De Jesús, GR, De Jesús, NR, Levy, RA, Leatherwood, C, Mandel, J & Bermas, B 2018, 'Challenging cases in rheumatic pregnancies', Rheumatology (Oxford, England), vol. 57, no. 5, pp. v18-v25. https://doi.org/10.1093/rheumatology/key172
Edens C, Rodrigues BC, Lacerda MI, Dos Santos FC, De Jesús GR, De Jesús NR et al. Challenging cases in rheumatic pregnancies. Rheumatology (Oxford, England). 2018 Jul 1;57(5):v18-v25. https://doi.org/10.1093/rheumatology/key172
Edens, Cuoghi ; Rodrigues, Bruna Costa ; Lacerda, Marcela Ignacchiti ; Dos Santos, Flavia Cunha ; De Jesús, Guilherme R. ; De Jesús, Nilson Ramires ; Levy, Roger A. ; Leatherwood, Cianna ; Mandel, Jess ; Bermas, Bonnie. / Challenging cases in rheumatic pregnancies. In: Rheumatology (Oxford, England). 2018 ; Vol. 57, No. 5. pp. v18-v25.
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