Abstract
Cyclic-di-GMP signaling is used by many bacteria to control biofilm formation. As biofilm formation is an important survival strategy for many bacteria, the synthesis and degradation of cyclic-di-GMP is tightly regulated by enzymes containing domains with conserved GGDEF and EAL sequence motifs, respectively. In this report we characterize a protein with both cyclase and phosphodiesterase activities and demonstrate that it contributes to secretion of the extracellular polysaccharide matrix, an important step in early biofilm formation.
Original language | English (US) |
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Pages (from-to) | 1561-1564 |
Number of pages | 4 |
Journal | Molecular BioSystems |
Volume | 6 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2010 |
Externally published | Yes |
ASJC Scopus subject areas
- Biotechnology
- Molecular Biology