Chemodivergent transformations of alkynyl imines

Anna W. Sromek, Arnold L. Rheingold, Donald J. Wink, Vladimir Gevorgyan

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

The investigation of cycloisomerization cascades of alkynyl imines towards pyrroles unexpectedly led to the development of chemodivergent routes towards quinolines and fused pyrrolines. It was found that, depending on the nature of the nitrogen substituent and choice of reagents, up to three different heterocyclic cores can be accessed from a common structural precursor.

Original languageEnglish (US)
Pages (from-to)2325-2328
Number of pages4
JournalSynlett
Issue number14
DOIs
StatePublished - Sep 1 2006
Externally publishedYes

Keywords

  • Alkynyl imines
  • Cycloaddition
  • Electrophilic cyclization
  • Heterocycles
  • Quinoline

ASJC Scopus subject areas

  • Organic Chemistry

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  • Cite this

    Sromek, A. W., Rheingold, A. L., Wink, D. J., & Gevorgyan, V. (2006). Chemodivergent transformations of alkynyl imines. Synlett, (14), 2325-2328. https://doi.org/10.1055/s-2006-949652