Chiral allene-containing phosphines in asymmetric catalysis

Feng Cai, Xiaotao Pu, Xiangbing Qi, Vincent Lynch, Akella Radha, Joseph M. Ready

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

We demonstrate that allenes, chiral 1,2-dienes, appended with basic functionality can serve as ligands for transition metals. We describe an allene-containing bisphosphine that, when coordinated to Rh(I), promotes the asymmetric addition of arylboronic acids to α-keto esters with high enantioselectivity. Solution and solid-state structural analysis reveals that one olefin of the allene can coordinate to transition metals, generating bi- and tridentate ligands.

Original languageEnglish (US)
Pages (from-to)18066-18069
Number of pages4
JournalJournal of the American Chemical Society
Volume133
Issue number45
DOIs
StatePublished - Nov 16 2011

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Phosphines
Catalysis
Transition metals
Ligands
Enantioselectivity
Metals
Structural analysis
Olefins
Keto Acids
Esters
Alkenes
Acids
propadiene

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Chiral allene-containing phosphines in asymmetric catalysis. / Cai, Feng; Pu, Xiaotao; Qi, Xiangbing; Lynch, Vincent; Radha, Akella; Ready, Joseph M.

In: Journal of the American Chemical Society, Vol. 133, No. 45, 16.11.2011, p. 18066-18069.

Research output: Contribution to journalArticle

Cai, Feng ; Pu, Xiaotao ; Qi, Xiangbing ; Lynch, Vincent ; Radha, Akella ; Ready, Joseph M. / Chiral allene-containing phosphines in asymmetric catalysis. In: Journal of the American Chemical Society. 2011 ; Vol. 133, No. 45. pp. 18066-18069.
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