Chronic Thromboembolic Pulmonary Hypertension in a Patient Heterozygous for both Factor V Leiden and the G20210A Prothrombin Mutation

George K. Kourgiannidis, Emmanuel S. Brilakis, Athanasios N. Manginas, Dennis V. Cokkinos

Research output: Contribution to journalArticle


Coagulation abnormalities have been implicated in the pathogenesis of chronic thromboembolic pulmonary hypertension, a serious disease with poor prognosis. We describe the first case of a 32-year-old heterozygous carrier of both factor V Leiden and the G20210A prothrombin mutation who developed severe chronic thromboembolic pulmonary hypertension, and was subsequently managed successfully with pulmonary thrombarterectomy.

Original languageEnglish (US)
Pages (from-to)218-221
Number of pages4
JournalHellenic Journal of Cardiology
Issue number3
StatePublished - May 1 2003



  • Chronic pulmonary embolism
  • Factor V Leiden
  • Prothrombin mutation G20210A
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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