Clinical and Technical Considerations for Brain PET Imaging for Dementia

Alzheimer’s Disease Neuroimaging Initiative

Research output: Contribution to journalReview article

Abstract

The number of cases of dementia has dramatically increased over the last decade. Imaging of the brain with PET has been used for many years, but in the past decade the radiopharmaceuticals and technology available for imaging dementia have vastly improved. In recent years, the U.S. Food and Drug Administration has approved 3 PET radiopharmaceuticals for detecting amyloid in brain, and tau PET radiopharmaceuticals are being investigated in clinical trials for use in dementia imaging. This paper will discuss different forms of dementia that can be imaged with PET, review common radiopharmaceuticals used for imaging dementia, and provide technical recommendations for performing the studies.

Original languageEnglish (US)
Pages (from-to)5-8
Number of pages4
JournalJournal of nuclear medicine technology
Volume48
Issue number1
DOIs
StatePublished - Mar 1 2020

Keywords

  • PET
  • amyloid
  • brain
  • tau

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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