Coenzyme A–mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice

Medicine & Life Sciences

• pyruvate dehydrogenase kinase 4 100%
• Coenzymes 76%
• Pyruvic Acid 63%
• Fats 44%
• Oxidoreductases 38%
• Coenzyme A 31%
• Fatty Acids 28%
• Diet 17%
• Mitochondria 13%
• Acetyl Coenzyme A 11%
• Fat-Restricted Diet 10%
• Glucose 10%
• Palmitates 10%
• Dietary Fats 10%
• Phosphoric Monoester Hydrolases 8%
• High Fat Diet 8%
• Meals 7%
• Nutrients 7%
• Phosphorylation 5%
• Heart 5%
• In Vitro Techniques 3%
• Proteins 3%

Chemical Compounds

• Coenzyme 63%
• Pyruvate 61%
• Metabolic 48%
• Flexibility 47%
• Fatty Acid 23%
• Acetyl-CoA 9%
• Nutrient 7%
• Oxidation Reaction 6%
• Glucose 5%
• Environment 4%
• Energy 3%
• Reduction 3%
• Protein 3%