Cold cuts added to the circadian smorgasbord of regulatory mechanisms

Research output: Contribution to journalArticlepeer-review

Abstract

In mammals, rhythms in body temperature help to entrain and synchronize circadian rhythms throughout the organism, and the cold-inducible RNA-binding protein (CIRBP) is one of the mediators of these daily temperature changes. CirbpmRNAexpression is regulated by the daily subtle rhythms in body temperature, and a new study by Gotic and colleagues (pp. 2005-2017) reveals a surprising and novel mechanism that involves temperature-dependent enhancement of splicing efficiency.

Original languageEnglish (US)
Pages (from-to)1909-1910
Number of pages2
JournalGenes and Development
Volume30
Issue number17
DOIs
StatePublished - Sep 1 2016

Keywords

  • Cirbp
  • Circadian rhythms
  • Splicing efficiency
  • Temperature

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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