Colorectal cancer in patients with inflammatory bowel disease

Parsia A. Vagefi, Walter E. Longo

Research output: Contribution to journalReview article

45 Scopus citations

Abstract

Patients with inflammatory bowel disease (IBD) are subject to increased risks for the development of colorectal cancer (CRC), risks that are attributed to the duration and anatomic extent of disease in patients with ulcerative colitis and Crohn's disease. Although IBD contributes only 1%-2% to all cases of CRC, the mortality rate in patients with a diagnosis of CRC in the setting of IBD is higher than for those afflicted with sporadic cases of CRC. Given the length of time from IBD onset to the development of CRC, surveillance continues to be widely practiced. Although still under development, novel techniques for the earlier detection of dysplastic lesions have moved to the forefront in an attempt to optimize surveillance strategies and decrease the risk of CRC development.

Original languageEnglish (US)
Pages (from-to)313-319
Number of pages7
JournalClinical colorectal cancer
Volume4
Issue number5
DOIs
StatePublished - Jan 2005

    Fingerprint

Keywords

  • Crohn's disease
  • Epithelial dysplasia
  • Permanent ileostomy
  • Proctocolectomy
  • Surgical prophylaxis
  • Surveillance strategies
  • Ulcerative colitis

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology

Cite this