Columbia University Assessment of Disability in Essential Tremor (CADET): Methodological issues in essential tremor research

K. J. Wendt, S. M. Albert, S. L. Pullman, F. R. Schneier, E. D. Louis

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Essential tremor (ET) is one of the most prevalent neurological disorders, affecting between 0.4 and 3.9% of the population. As there have been few studies of the functional impact of ET, knowledge of this area is limited. One study relied on subjective reports of tremor severity while a second focused on issues relating to treatment. Knowledge about the functional impact of ET is important for the valid assessment of efficacy in therapeutic trials as well as the diagnosis of ET in genetic and epidemiological studies. In order to examine the issue of functional disability in ET in greater detail, we designed the Columbia University Assessment of Disability in Essential Tremor (CADET). The critical elements of the study design have not been consistently applied to ET research to date. We describe this novel study.

Original languageEnglish (US)
Pages (from-to)17-23
Number of pages7
JournalParkinsonism and Related Disorders
Volume6
Issue number1
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Keywords

  • Disability
  • Epidemiology
  • Essential tremor
  • Function

ASJC Scopus subject areas

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology

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