Combined thrombolytic therapy for prosthetic mitral valve thrombosis

Charles M T Jost, Clyde W. Yancy, W. Steves Ring

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Prosthetic valve thrombosis is associated with high mortality. The treatment of choice remains operation. This is a case report of the successful combination therapy of tissue plasminogen activator and urokinase for an isolated thrombosed prosthetic mitral valve in a postpartum patient in whom operation was thought to carry an unacceptable risk. Combined thrombolytic therapy or therapy with a single agent with a long half-life and a prolonged infusion time is suggested as an emergent treatment option for prosthetic mitral valve thrombosis.

Original languageEnglish (US)
Pages (from-to)159-161
Number of pages3
JournalThe Annals of Thoracic Surgery
Volume55
Issue number1
DOIs
StatePublished - 1993

Fingerprint

Thrombolytic Therapy
Mitral Valve
Thrombosis
Urokinase-Type Plasminogen Activator
Tissue Plasminogen Activator
Therapeutics
Postpartum Period
Half-Life
Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Combined thrombolytic therapy for prosthetic mitral valve thrombosis. / Jost, Charles M T; Yancy, Clyde W.; Ring, W. Steves.

In: The Annals of Thoracic Surgery, Vol. 55, No. 1, 1993, p. 159-161.

Research output: Contribution to journalArticle

Jost, Charles M T ; Yancy, Clyde W. ; Ring, W. Steves. / Combined thrombolytic therapy for prosthetic mitral valve thrombosis. In: The Annals of Thoracic Surgery. 1993 ; Vol. 55, No. 1. pp. 159-161.
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