Comparing the sensation of common donor site regions for autologous breast reconstruction to that of a healthy breast

Anouk J.M. Cornelissen, Jop Beugels, Arno Lataster, Esther M. Heuts, Shai M. Rozen, Aldona J. Spiegel, René R.W.J. van der Hulst, Stefania M.H. Tuinder

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction: Autologous breast reconstruction has become the standard care for breast cancer patients. Although excellent cosmetic results can be achieved, most reconstructed breasts fail to regain normal sensation. Nerve coaptation of the flap has been suggested to improve sensation; the effect of the donor flap native sensory threshold on the degree of sensory restoration is yet to be determined. The aim of this study is to evaluate the differences in sensation between various potential donor site regions in comparison to the sensation of the healthy breast. Patients and methods: A cross-sectional study in healthy women was performed in the Maastricht University Medical Centre. Monofilaments were used to measure sensation in the breast and at different flap donor sites: deep inferior epigastric perforator (DIEP), lateral thigh perforator (LTP), profunda artery perforator (PAP), superior gluteal artery perforator (SGAP) and transverse musculocutaneous gracilis (TMG) flaps. The Wilcoxon signed rank test was used to analyse statistical significance in sensation. Results: Fifty women with a mean age of 49 ± 2.72 years and mean BMI of 26.14 ± 0.89 kg/m2 were included in the study. The median monofilament value of the normal breasts was 2.97(2.56-3.55). The median monofilament value of each donor site and p value when compared to the healthy breast were as follows: DIEP flap, 2.62 (2.36-3.22) p < 0.01; LTP flap, 3.61 (2.83-4.08) p <0.01; PAP flap, 3.09 (2.67-3.5) p = 0.97; SGAP flap, 3.22 (2.64-3.87) p = 0.01; and TMG flap, 3.03 (2.6-3.47) p = 0.69. Conclusions: There is a significant difference in sensation between the various donor site regions for breast reconstruction and the healthy breast. This may be taken into consideration for donor site selection.

Original languageEnglish (US)
JournalJournal of Plastic, Reconstructive and Aesthetic Surgery
DOIs
StateAccepted/In press - 2017

Fingerprint

Mammaplasty
Breast
Perforator Flap
Tissue Donors
Arteries
Myocutaneous Flap
Thigh
Sensory Thresholds
Donor Selection
Nonparametric Statistics
Cosmetics
Reference Values
Cross-Sectional Studies
Breast Neoplasms

Keywords

  • Breast reconstruction
  • Donor site
  • Innervation
  • Microsurgery
  • Nerve coaptation
  • Sensation

ASJC Scopus subject areas

  • Surgery

Cite this

Comparing the sensation of common donor site regions for autologous breast reconstruction to that of a healthy breast. / Cornelissen, Anouk J.M.; Beugels, Jop; Lataster, Arno; Heuts, Esther M.; Rozen, Shai M.; Spiegel, Aldona J.; van der Hulst, René R.W.J.; Tuinder, Stefania M.H.

In: Journal of Plastic, Reconstructive and Aesthetic Surgery, 2017.

Research output: Contribution to journalArticle

Cornelissen, Anouk J.M. ; Beugels, Jop ; Lataster, Arno ; Heuts, Esther M. ; Rozen, Shai M. ; Spiegel, Aldona J. ; van der Hulst, René R.W.J. ; Tuinder, Stefania M.H. / Comparing the sensation of common donor site regions for autologous breast reconstruction to that of a healthy breast. In: Journal of Plastic, Reconstructive and Aesthetic Surgery. 2017.
@article{c991f466623741dfa62093c502816b42,
title = "Comparing the sensation of common donor site regions for autologous breast reconstruction to that of a healthy breast",
abstract = "Introduction: Autologous breast reconstruction has become the standard care for breast cancer patients. Although excellent cosmetic results can be achieved, most reconstructed breasts fail to regain normal sensation. Nerve coaptation of the flap has been suggested to improve sensation; the effect of the donor flap native sensory threshold on the degree of sensory restoration is yet to be determined. The aim of this study is to evaluate the differences in sensation between various potential donor site regions in comparison to the sensation of the healthy breast. Patients and methods: A cross-sectional study in healthy women was performed in the Maastricht University Medical Centre. Monofilaments were used to measure sensation in the breast and at different flap donor sites: deep inferior epigastric perforator (DIEP), lateral thigh perforator (LTP), profunda artery perforator (PAP), superior gluteal artery perforator (SGAP) and transverse musculocutaneous gracilis (TMG) flaps. The Wilcoxon signed rank test was used to analyse statistical significance in sensation. Results: Fifty women with a mean age of 49 ± 2.72 years and mean BMI of 26.14 ± 0.89 kg/m2 were included in the study. The median monofilament value of the normal breasts was 2.97(2.56-3.55). The median monofilament value of each donor site and p value when compared to the healthy breast were as follows: DIEP flap, 2.62 (2.36-3.22) p < 0.01; LTP flap, 3.61 (2.83-4.08) p <0.01; PAP flap, 3.09 (2.67-3.5) p = 0.97; SGAP flap, 3.22 (2.64-3.87) p = 0.01; and TMG flap, 3.03 (2.6-3.47) p = 0.69. Conclusions: There is a significant difference in sensation between the various donor site regions for breast reconstruction and the healthy breast. This may be taken into consideration for donor site selection.",
keywords = "Breast reconstruction, Donor site, Innervation, Microsurgery, Nerve coaptation, Sensation",
author = "Cornelissen, {Anouk J.M.} and Jop Beugels and Arno Lataster and Heuts, {Esther M.} and Rozen, {Shai M.} and Spiegel, {Aldona J.} and {van der Hulst}, {Ren{\'e} R.W.J.} and Tuinder, {Stefania M.H.}",
year = "2017",
doi = "10.1016/j.bjps.2017.09.011",
language = "English (US)",
journal = "Journal of Plastic, Reconstructive and Aesthetic Surgery",
issn = "1748-6815",
publisher = "Churchill Livingstone",

}

TY - JOUR

T1 - Comparing the sensation of common donor site regions for autologous breast reconstruction to that of a healthy breast

AU - Cornelissen, Anouk J.M.

AU - Beugels, Jop

AU - Lataster, Arno

AU - Heuts, Esther M.

AU - Rozen, Shai M.

AU - Spiegel, Aldona J.

AU - van der Hulst, René R.W.J.

AU - Tuinder, Stefania M.H.

PY - 2017

Y1 - 2017

N2 - Introduction: Autologous breast reconstruction has become the standard care for breast cancer patients. Although excellent cosmetic results can be achieved, most reconstructed breasts fail to regain normal sensation. Nerve coaptation of the flap has been suggested to improve sensation; the effect of the donor flap native sensory threshold on the degree of sensory restoration is yet to be determined. The aim of this study is to evaluate the differences in sensation between various potential donor site regions in comparison to the sensation of the healthy breast. Patients and methods: A cross-sectional study in healthy women was performed in the Maastricht University Medical Centre. Monofilaments were used to measure sensation in the breast and at different flap donor sites: deep inferior epigastric perforator (DIEP), lateral thigh perforator (LTP), profunda artery perforator (PAP), superior gluteal artery perforator (SGAP) and transverse musculocutaneous gracilis (TMG) flaps. The Wilcoxon signed rank test was used to analyse statistical significance in sensation. Results: Fifty women with a mean age of 49 ± 2.72 years and mean BMI of 26.14 ± 0.89 kg/m2 were included in the study. The median monofilament value of the normal breasts was 2.97(2.56-3.55). The median monofilament value of each donor site and p value when compared to the healthy breast were as follows: DIEP flap, 2.62 (2.36-3.22) p < 0.01; LTP flap, 3.61 (2.83-4.08) p <0.01; PAP flap, 3.09 (2.67-3.5) p = 0.97; SGAP flap, 3.22 (2.64-3.87) p = 0.01; and TMG flap, 3.03 (2.6-3.47) p = 0.69. Conclusions: There is a significant difference in sensation between the various donor site regions for breast reconstruction and the healthy breast. This may be taken into consideration for donor site selection.

AB - Introduction: Autologous breast reconstruction has become the standard care for breast cancer patients. Although excellent cosmetic results can be achieved, most reconstructed breasts fail to regain normal sensation. Nerve coaptation of the flap has been suggested to improve sensation; the effect of the donor flap native sensory threshold on the degree of sensory restoration is yet to be determined. The aim of this study is to evaluate the differences in sensation between various potential donor site regions in comparison to the sensation of the healthy breast. Patients and methods: A cross-sectional study in healthy women was performed in the Maastricht University Medical Centre. Monofilaments were used to measure sensation in the breast and at different flap donor sites: deep inferior epigastric perforator (DIEP), lateral thigh perforator (LTP), profunda artery perforator (PAP), superior gluteal artery perforator (SGAP) and transverse musculocutaneous gracilis (TMG) flaps. The Wilcoxon signed rank test was used to analyse statistical significance in sensation. Results: Fifty women with a mean age of 49 ± 2.72 years and mean BMI of 26.14 ± 0.89 kg/m2 were included in the study. The median monofilament value of the normal breasts was 2.97(2.56-3.55). The median monofilament value of each donor site and p value when compared to the healthy breast were as follows: DIEP flap, 2.62 (2.36-3.22) p < 0.01; LTP flap, 3.61 (2.83-4.08) p <0.01; PAP flap, 3.09 (2.67-3.5) p = 0.97; SGAP flap, 3.22 (2.64-3.87) p = 0.01; and TMG flap, 3.03 (2.6-3.47) p = 0.69. Conclusions: There is a significant difference in sensation between the various donor site regions for breast reconstruction and the healthy breast. This may be taken into consideration for donor site selection.

KW - Breast reconstruction

KW - Donor site

KW - Innervation

KW - Microsurgery

KW - Nerve coaptation

KW - Sensation

UR - http://www.scopus.com/inward/record.url?scp=85031499978&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85031499978&partnerID=8YFLogxK

U2 - 10.1016/j.bjps.2017.09.011

DO - 10.1016/j.bjps.2017.09.011

M3 - Article

C2 - 29050873

AN - SCOPUS:85031499978

JO - Journal of Plastic, Reconstructive and Aesthetic Surgery

JF - Journal of Plastic, Reconstructive and Aesthetic Surgery

SN - 1748-6815

ER -