Comparison of slot scanning digital mammography system with full-field digital mammography system

Chao Jen Lai, Chris C. Shaw, William Geiser, Lingyun Chen, Elsa Arribas, Tanya Stephens, Paul L. Davis, Geetha P. Ayyar, Basak E. Dogan, Victoria A. Nguyen, Gary J. Whitman, Wei T. Yang

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The purpose of this study was to evaluate and compare microcalcification detectability of two commercial full-field digital mammography (DM) systems. The first unit was a flat panel based DM system (FFDM) which employed an anti-scatter grid method to reject scatter, and the second unit was a charge-coupled device-based DM system (SSDM) which used scanning slot imaging geometry to reduce scatter radiation. Both systems have comparable scatter-to-primary ratios. In this study, 125-160 and 200-250 μm calcium carbonate grains were used to simulate microcalcifications and imaged by both DM systems. The calcium carbonate grains were overlapped with a 5-cm -thick 50% adipose/50% glandular simulated breast tissue slab and an anthropomorphic breast phantom (RMI 165, Gammex) for imaging at two different mean glandular dose levels: 0.87 and 1.74 mGy. A reading study was conducted with seven board certified mammographers with images displayed on review workstations. A five-point confidence level rating was used to score each detection task. Receiver operating characteristic (ROC) analysis was performed and the area under the ROC curve (Az) was used to quantify and compare the performances of these two systems. The results showed that with the simulated breast tissue slab (uniform background), the SSDM system resulted in higher Az 's than the FFDM system at both MGD levels with the difference statistically significant at 0.87 mGy only. With the anthropomorphic breast phantom (tissue structure background), the SSDM system performed better than the FFDM system at 0.87 mGy but worse at 1.74 mGy. However, the differences were not found to be statistically significant.

Original languageEnglish (US)
Pages (from-to)2339-2346
Number of pages8
JournalMedical Physics
Volume35
Issue number6
DOIs
StatePublished - Jan 1 2008

Fingerprint

Mammography
Breast
Calcinosis
Calcium Carbonate
ROC Curve
Reading
Radiation
Equipment and Supplies

Keywords

  • Digital mammography
  • Mean glandular dose
  • Microcalcifications
  • ROC
  • Slot scanning

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Lai, C. J., Shaw, C. C., Geiser, W., Chen, L., Arribas, E., Stephens, T., ... Yang, W. T. (2008). Comparison of slot scanning digital mammography system with full-field digital mammography system. Medical Physics, 35(6), 2339-2346. https://doi.org/10.1118/1.2919768

Comparison of slot scanning digital mammography system with full-field digital mammography system. / Lai, Chao Jen; Shaw, Chris C.; Geiser, William; Chen, Lingyun; Arribas, Elsa; Stephens, Tanya; Davis, Paul L.; Ayyar, Geetha P.; Dogan, Basak E.; Nguyen, Victoria A.; Whitman, Gary J.; Yang, Wei T.

In: Medical Physics, Vol. 35, No. 6, 01.01.2008, p. 2339-2346.

Research output: Contribution to journalArticle

Lai, CJ, Shaw, CC, Geiser, W, Chen, L, Arribas, E, Stephens, T, Davis, PL, Ayyar, GP, Dogan, BE, Nguyen, VA, Whitman, GJ & Yang, WT 2008, 'Comparison of slot scanning digital mammography system with full-field digital mammography system', Medical Physics, vol. 35, no. 6, pp. 2339-2346. https://doi.org/10.1118/1.2919768
Lai, Chao Jen ; Shaw, Chris C. ; Geiser, William ; Chen, Lingyun ; Arribas, Elsa ; Stephens, Tanya ; Davis, Paul L. ; Ayyar, Geetha P. ; Dogan, Basak E. ; Nguyen, Victoria A. ; Whitman, Gary J. ; Yang, Wei T. / Comparison of slot scanning digital mammography system with full-field digital mammography system. In: Medical Physics. 2008 ; Vol. 35, No. 6. pp. 2339-2346.
@article{a2804746bcc2436cbbcefe29f7b8214c,
title = "Comparison of slot scanning digital mammography system with full-field digital mammography system",
abstract = "The purpose of this study was to evaluate and compare microcalcification detectability of two commercial full-field digital mammography (DM) systems. The first unit was a flat panel based DM system (FFDM) which employed an anti-scatter grid method to reject scatter, and the second unit was a charge-coupled device-based DM system (SSDM) which used scanning slot imaging geometry to reduce scatter radiation. Both systems have comparable scatter-to-primary ratios. In this study, 125-160 and 200-250 μm calcium carbonate grains were used to simulate microcalcifications and imaged by both DM systems. The calcium carbonate grains were overlapped with a 5-cm -thick 50{\%} adipose/50{\%} glandular simulated breast tissue slab and an anthropomorphic breast phantom (RMI 165, Gammex) for imaging at two different mean glandular dose levels: 0.87 and 1.74 mGy. A reading study was conducted with seven board certified mammographers with images displayed on review workstations. A five-point confidence level rating was used to score each detection task. Receiver operating characteristic (ROC) analysis was performed and the area under the ROC curve (Az) was used to quantify and compare the performances of these two systems. The results showed that with the simulated breast tissue slab (uniform background), the SSDM system resulted in higher Az 's than the FFDM system at both MGD levels with the difference statistically significant at 0.87 mGy only. With the anthropomorphic breast phantom (tissue structure background), the SSDM system performed better than the FFDM system at 0.87 mGy but worse at 1.74 mGy. However, the differences were not found to be statistically significant.",
keywords = "Digital mammography, Mean glandular dose, Microcalcifications, ROC, Slot scanning",
author = "Lai, {Chao Jen} and Shaw, {Chris C.} and William Geiser and Lingyun Chen and Elsa Arribas and Tanya Stephens and Davis, {Paul L.} and Ayyar, {Geetha P.} and Dogan, {Basak E.} and Nguyen, {Victoria A.} and Whitman, {Gary J.} and Yang, {Wei T.}",
year = "2008",
month = "1",
day = "1",
doi = "10.1118/1.2919768",
language = "English (US)",
volume = "35",
pages = "2339--2346",
journal = "Medical Physics",
issn = "0094-2405",
publisher = "AAPM - American Association of Physicists in Medicine",
number = "6",

}

TY - JOUR

T1 - Comparison of slot scanning digital mammography system with full-field digital mammography system

AU - Lai, Chao Jen

AU - Shaw, Chris C.

AU - Geiser, William

AU - Chen, Lingyun

AU - Arribas, Elsa

AU - Stephens, Tanya

AU - Davis, Paul L.

AU - Ayyar, Geetha P.

AU - Dogan, Basak E.

AU - Nguyen, Victoria A.

AU - Whitman, Gary J.

AU - Yang, Wei T.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - The purpose of this study was to evaluate and compare microcalcification detectability of two commercial full-field digital mammography (DM) systems. The first unit was a flat panel based DM system (FFDM) which employed an anti-scatter grid method to reject scatter, and the second unit was a charge-coupled device-based DM system (SSDM) which used scanning slot imaging geometry to reduce scatter radiation. Both systems have comparable scatter-to-primary ratios. In this study, 125-160 and 200-250 μm calcium carbonate grains were used to simulate microcalcifications and imaged by both DM systems. The calcium carbonate grains were overlapped with a 5-cm -thick 50% adipose/50% glandular simulated breast tissue slab and an anthropomorphic breast phantom (RMI 165, Gammex) for imaging at two different mean glandular dose levels: 0.87 and 1.74 mGy. A reading study was conducted with seven board certified mammographers with images displayed on review workstations. A five-point confidence level rating was used to score each detection task. Receiver operating characteristic (ROC) analysis was performed and the area under the ROC curve (Az) was used to quantify and compare the performances of these two systems. The results showed that with the simulated breast tissue slab (uniform background), the SSDM system resulted in higher Az 's than the FFDM system at both MGD levels with the difference statistically significant at 0.87 mGy only. With the anthropomorphic breast phantom (tissue structure background), the SSDM system performed better than the FFDM system at 0.87 mGy but worse at 1.74 mGy. However, the differences were not found to be statistically significant.

AB - The purpose of this study was to evaluate and compare microcalcification detectability of two commercial full-field digital mammography (DM) systems. The first unit was a flat panel based DM system (FFDM) which employed an anti-scatter grid method to reject scatter, and the second unit was a charge-coupled device-based DM system (SSDM) which used scanning slot imaging geometry to reduce scatter radiation. Both systems have comparable scatter-to-primary ratios. In this study, 125-160 and 200-250 μm calcium carbonate grains were used to simulate microcalcifications and imaged by both DM systems. The calcium carbonate grains were overlapped with a 5-cm -thick 50% adipose/50% glandular simulated breast tissue slab and an anthropomorphic breast phantom (RMI 165, Gammex) for imaging at two different mean glandular dose levels: 0.87 and 1.74 mGy. A reading study was conducted with seven board certified mammographers with images displayed on review workstations. A five-point confidence level rating was used to score each detection task. Receiver operating characteristic (ROC) analysis was performed and the area under the ROC curve (Az) was used to quantify and compare the performances of these two systems. The results showed that with the simulated breast tissue slab (uniform background), the SSDM system resulted in higher Az 's than the FFDM system at both MGD levels with the difference statistically significant at 0.87 mGy only. With the anthropomorphic breast phantom (tissue structure background), the SSDM system performed better than the FFDM system at 0.87 mGy but worse at 1.74 mGy. However, the differences were not found to be statistically significant.

KW - Digital mammography

KW - Mean glandular dose

KW - Microcalcifications

KW - ROC

KW - Slot scanning

UR - http://www.scopus.com/inward/record.url?scp=44349145128&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=44349145128&partnerID=8YFLogxK

U2 - 10.1118/1.2919768

DO - 10.1118/1.2919768

M3 - Article

C2 - 18649467

AN - SCOPUS:44349145128

VL - 35

SP - 2339

EP - 2346

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 6

ER -