Comparison of Target Registration Errors for Multiple Image-Guided Techniques in Accelerated Partial Breast Irradiation

David P. Gierga, Marco Riboldi, Julie C. Turcotte, Greg C. Sharp, Steve B. Jiang, Alphonse G. Taghian, George T Y Chen

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

Purpose: External beam accelerated partial breast irradiation requires accurate localization of the target volume for each treatment fraction. Using the concept of target registration error (TRE), the performance of several methods of target localization was compared. Methods and Materials: Twelve patients who underwent external beam accelerated partial breast irradiation were included in this study. TRE was quantified for four methods of image guidance: standard laser-based setup, kilovoltage imaging of the chest wall, kilovoltage imaging of surgically implanted clips, and three-dimensional surface imaging of the breast. The use of a reference surface created from a free-breathing computed tomography scan and a reference surface directly captured with three-dimensional video imaging were compared. The effects of respiratory motion were also considered, and gating was used for 8 of 12 patients. Results: The median value of the TRE for the laser, chest wall, and clip alignment was 7.1 mm (n = 94), 5.4 mm (n = 81), and 2.4 mm (n = 93), respectively. The median TRE for gated surface imaging based on the first fraction reference surface was 3.2 mm (n = 49), and the TRE for gated surface imaging using the computed tomography-based reference surface was 4.9 mm (n = 56). The TRE for nongated surface imaging using the first fraction reference surface was 6.2 mm (n = 25). Conclusions: The TRE of surface imaging using a reference surface directly captured with three-dimensional video and the TRE for clip-based setup were within 1 mm. Gated capture is important for surface imaging to reduce the effects of respiratory motion in accelerated partial breast irradiation.

Original languageEnglish (US)
Pages (from-to)1239-1246
Number of pages8
JournalInternational Journal of Radiation Oncology Biology Physics
Volume70
Issue number4
DOIs
StatePublished - Mar 15 2008

Fingerprint

breast
Breast
Surgical Instruments
irradiation
Three-Dimensional Imaging
Thoracic Wall
Lasers
Tomography
clips
Respiration
chest
tomography
breathing
lasers
Therapeutics
alignment

Keywords

  • Image guidance
  • Partial breast irradiation
  • Surface imaging
  • Target registration error
  • X-ray localization

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiation

Cite this

Comparison of Target Registration Errors for Multiple Image-Guided Techniques in Accelerated Partial Breast Irradiation. / Gierga, David P.; Riboldi, Marco; Turcotte, Julie C.; Sharp, Greg C.; Jiang, Steve B.; Taghian, Alphonse G.; Chen, George T Y.

In: International Journal of Radiation Oncology Biology Physics, Vol. 70, No. 4, 15.03.2008, p. 1239-1246.

Research output: Contribution to journalArticle

Gierga, David P. ; Riboldi, Marco ; Turcotte, Julie C. ; Sharp, Greg C. ; Jiang, Steve B. ; Taghian, Alphonse G. ; Chen, George T Y. / Comparison of Target Registration Errors for Multiple Image-Guided Techniques in Accelerated Partial Breast Irradiation. In: International Journal of Radiation Oncology Biology Physics. 2008 ; Vol. 70, No. 4. pp. 1239-1246.
@article{ba9ed87fbf934a978de3519f73666c26,
title = "Comparison of Target Registration Errors for Multiple Image-Guided Techniques in Accelerated Partial Breast Irradiation",
abstract = "Purpose: External beam accelerated partial breast irradiation requires accurate localization of the target volume for each treatment fraction. Using the concept of target registration error (TRE), the performance of several methods of target localization was compared. Methods and Materials: Twelve patients who underwent external beam accelerated partial breast irradiation were included in this study. TRE was quantified for four methods of image guidance: standard laser-based setup, kilovoltage imaging of the chest wall, kilovoltage imaging of surgically implanted clips, and three-dimensional surface imaging of the breast. The use of a reference surface created from a free-breathing computed tomography scan and a reference surface directly captured with three-dimensional video imaging were compared. The effects of respiratory motion were also considered, and gating was used for 8 of 12 patients. Results: The median value of the TRE for the laser, chest wall, and clip alignment was 7.1 mm (n = 94), 5.4 mm (n = 81), and 2.4 mm (n = 93), respectively. The median TRE for gated surface imaging based on the first fraction reference surface was 3.2 mm (n = 49), and the TRE for gated surface imaging using the computed tomography-based reference surface was 4.9 mm (n = 56). The TRE for nongated surface imaging using the first fraction reference surface was 6.2 mm (n = 25). Conclusions: The TRE of surface imaging using a reference surface directly captured with three-dimensional video and the TRE for clip-based setup were within 1 mm. Gated capture is important for surface imaging to reduce the effects of respiratory motion in accelerated partial breast irradiation.",
keywords = "Image guidance, Partial breast irradiation, Surface imaging, Target registration error, X-ray localization",
author = "Gierga, {David P.} and Marco Riboldi and Turcotte, {Julie C.} and Sharp, {Greg C.} and Jiang, {Steve B.} and Taghian, {Alphonse G.} and Chen, {George T Y}",
year = "2008",
month = "3",
day = "15",
doi = "10.1016/j.ijrobp.2007.11.020",
language = "English (US)",
volume = "70",
pages = "1239--1246",
journal = "International Journal of Radiation Oncology Biology Physics",
issn = "0360-3016",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Comparison of Target Registration Errors for Multiple Image-Guided Techniques in Accelerated Partial Breast Irradiation

AU - Gierga, David P.

AU - Riboldi, Marco

AU - Turcotte, Julie C.

AU - Sharp, Greg C.

AU - Jiang, Steve B.

AU - Taghian, Alphonse G.

AU - Chen, George T Y

PY - 2008/3/15

Y1 - 2008/3/15

N2 - Purpose: External beam accelerated partial breast irradiation requires accurate localization of the target volume for each treatment fraction. Using the concept of target registration error (TRE), the performance of several methods of target localization was compared. Methods and Materials: Twelve patients who underwent external beam accelerated partial breast irradiation were included in this study. TRE was quantified for four methods of image guidance: standard laser-based setup, kilovoltage imaging of the chest wall, kilovoltage imaging of surgically implanted clips, and three-dimensional surface imaging of the breast. The use of a reference surface created from a free-breathing computed tomography scan and a reference surface directly captured with three-dimensional video imaging were compared. The effects of respiratory motion were also considered, and gating was used for 8 of 12 patients. Results: The median value of the TRE for the laser, chest wall, and clip alignment was 7.1 mm (n = 94), 5.4 mm (n = 81), and 2.4 mm (n = 93), respectively. The median TRE for gated surface imaging based on the first fraction reference surface was 3.2 mm (n = 49), and the TRE for gated surface imaging using the computed tomography-based reference surface was 4.9 mm (n = 56). The TRE for nongated surface imaging using the first fraction reference surface was 6.2 mm (n = 25). Conclusions: The TRE of surface imaging using a reference surface directly captured with three-dimensional video and the TRE for clip-based setup were within 1 mm. Gated capture is important for surface imaging to reduce the effects of respiratory motion in accelerated partial breast irradiation.

AB - Purpose: External beam accelerated partial breast irradiation requires accurate localization of the target volume for each treatment fraction. Using the concept of target registration error (TRE), the performance of several methods of target localization was compared. Methods and Materials: Twelve patients who underwent external beam accelerated partial breast irradiation were included in this study. TRE was quantified for four methods of image guidance: standard laser-based setup, kilovoltage imaging of the chest wall, kilovoltage imaging of surgically implanted clips, and three-dimensional surface imaging of the breast. The use of a reference surface created from a free-breathing computed tomography scan and a reference surface directly captured with three-dimensional video imaging were compared. The effects of respiratory motion were also considered, and gating was used for 8 of 12 patients. Results: The median value of the TRE for the laser, chest wall, and clip alignment was 7.1 mm (n = 94), 5.4 mm (n = 81), and 2.4 mm (n = 93), respectively. The median TRE for gated surface imaging based on the first fraction reference surface was 3.2 mm (n = 49), and the TRE for gated surface imaging using the computed tomography-based reference surface was 4.9 mm (n = 56). The TRE for nongated surface imaging using the first fraction reference surface was 6.2 mm (n = 25). Conclusions: The TRE of surface imaging using a reference surface directly captured with three-dimensional video and the TRE for clip-based setup were within 1 mm. Gated capture is important for surface imaging to reduce the effects of respiratory motion in accelerated partial breast irradiation.

KW - Image guidance

KW - Partial breast irradiation

KW - Surface imaging

KW - Target registration error

KW - X-ray localization

UR - http://www.scopus.com/inward/record.url?scp=39749161503&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=39749161503&partnerID=8YFLogxK

U2 - 10.1016/j.ijrobp.2007.11.020

DO - 10.1016/j.ijrobp.2007.11.020

M3 - Article

C2 - 18207662

AN - SCOPUS:39749161503

VL - 70

SP - 1239

EP - 1246

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

SN - 0360-3016

IS - 4

ER -