Abstract
Biological tissues are complex time-dependent materials, and the best choice of the appropriate time-dependent constitutive description is not evident. This report reviews two constitutive models (a modified Kelvin model and a two-network Ogden-Boyce model) in the characterization of the passive stress-strain properties of laryngeal tissue under tensile deformation. The two models are compared, as are the automated methods for parameterization of tissue stress-strain data (a brute force vs. a common optimization method). Sensitivity (error curves) of parameters from both models and the optimized parameter set are calculated and contrast by optimizing to the same tissue stress-strain data. Both models adequately characterized empirical stress-strain datasets and could be used to recreate a good likeness of the data. Nevertheless, parameters in both models were sensitive to measurement errors or uncertainties in stress-strain, which would greatly hinder the confidence in those parameters. The modified Kelvin model emerges as a potential better choice for phonation models which use a tissue model as one component, or for general comparisons of the mechanical properties of one type of tissue to another (e.g.; axial stress nonlinearity). In contrast, the Ogden-Boyce model would be more appropriate to provide a basic understanding of the tissue's mechanical response with better insights into the tissue's physical characteristics in terms of standard engineering metrics such as shear modulus and viscosity.
Original language | English (US) |
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Pages (from-to) | 179-196 |
Number of pages | 18 |
Journal | Mechanics of Time-Dependent Materials |
Volume | 18 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2014 |
Keywords
- Constitutive models
- Parameter identification
- Sensitivity study
- Vocal fold biomechanics
ASJC Scopus subject areas
- General Chemical Engineering
- General Materials Science
- Aerospace Engineering
- Mechanical Engineering