Concentrations of erythromycin in serum and tonsil: comparison of the estolate and ethyl succinate suspensions

Paul S. Lietman; Charles M. Ginsburg; George H. McCracken; M. C. Culbertson

doi:10.1016/S0022-3476(76)80622-1

Concentrations of erythromycin in serum and tonsil: comparison of the estolate and ethyl succinate suspensions

Paul S. Lietman, Charles M. Ginsburg, George H. McCracken, M. C. Culbertson

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Abstract

Concentrations of erythromycin were measured in serum and tonsil from children who had received either the estolate or ethyl succinate suspension before surgery. The in vitro assay measured total erythromycin activity against a group A beta hemolytic streptococcus. Levels of erythromycin in serum and tonsil after single and multiple doses of the estolate were significantly higher than those after administration of the ethyl succinate. The therapeutic implications of these findings are unknown.

Original language	English (US)
Pages (from-to)	1011-1013
Number of pages	3
Journal	The Journal of pediatrics
Volume	89
Issue number	6
DOIs	https://doi.org/10.1016/S0022-3476(76)80622-1
State	Published - Dec 1976

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ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Cite this

Lietman, P. S., Ginsburg, C. M., McCracken, G. H., & Culbertson, M. C. (1976). Concentrations of erythromycin in serum and tonsil: comparison of the estolate and ethyl succinate suspensions. The Journal of pediatrics, 89(6), 1011-1013. https://doi.org/10.1016/S0022-3476(76)80622-1

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10.1016/S0022-3476(76)80622-1