Conditioned taste aversion using four different means to deliver sucrose to rats

Jun Yamamoto, Nadine Fresquet, Guy Sandner

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

A solution of sucrose either to be drunk from a drinking tube - self-drinking procedure (SD) - or perfused intraorally as a consequence of nose-pokes - self-administration procedure (SA) - or perfused as a consequence of licking an empty tube (LA) - was paired with an LiCl-induced malaise in rats. The effects were compared to those of a procedure consisting of intraoral administration (IO) of sucrose not contingent to any specific action of the rat. Similar levels of conditioned taste aversion (CTA) were obtained but extinction in the IO procedure was quicker than in the SA procedure, which was itself quicker than in the SD procedure. Extinctions in the IO and LA procedures resembled one another and were quicker than in the SD procedure. A step towards deciding between several explanatory hypotheses of these differences was made by conducting two more experiments. The third experiment was based on reinstatement, or not, of the conditioning procedure for the test after standard IO extinction. CTA was produced only when SD was used both at conditioning and test. A fourth experiment was based on latent inhibition where the procedure was changed, or not, between preexposure and conditioning. Latent inhibition was absent only when the rats had been preexposed to sucrose with the SA procedure and conditioned with the SD procedure.

Original languageEnglish (US)
Pages (from-to)387-396
Number of pages10
JournalPhysiology and Behavior
Volume75
Issue number3
DOIs
StatePublished - Jan 1 2002

Keywords

  • Classical conditioning
  • Conditioned taste aversion
  • Instrumental learning
  • Latent inhibition
  • Long-Evans rats
  • Models of schizophrenia
  • Renewal after extinction

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

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