Controlled clinical comparison of new pediatric medium with adsorbent polymeric beads (PF Plus) versus charcoal-containing PF medium in the bact/alert blood culture system

Christopher D. Doern, Stanley Mirrett, Diane Halstead, Joan Abid, Pamela Okada, L. Barth Reller

Research output: Contribution to journalArticle

8 Scopus citations


We conducted a controlled clinical comparison of PF Plus, the new pediatric medium with adsorbent polymeric beads, versus the charcoal-containing PF medium in the BacT/Alert blood culture system. A total of 2,381 pediatric cultures were enrolled, and 1,703 (71.5%) were deemed to be compliant and acceptable for analysis. Seventy-two cultures (4.2%) had a positive result with 80 clinically significant microorganisms. The results showed that the PF Plus medium yielded more clinically significant microorganisms than the BacT/Alert system (P<0.05). In addition, the PF Plus bottle yielded positive results an average of 5.0 h earlier than the PF bottle for compliant clinically significant cultures (18.3 h versus 23.2 h, P0.004). PF Plus is an improved medium for detecting microorganisms that cause pediatric bloodstream infections.

Original languageEnglish (US)
Pages (from-to)1898-1900
Number of pages3
JournalJournal of clinical microbiology
Issue number6
StatePublished - Jun 2014


ASJC Scopus subject areas

  • Microbiology (medical)

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