Coronary anomalies assessed by whole-heart isotropic 3D magnetic resonance imaging for cardiac morphology in congenital heart disease

Philipp Beerbaum, Samir Sarikouch, Kai Thorsten Laser, Gerald Greil, Wolfgang Burchert, Hermann Körperich

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Conclusion: Isotropic whole-heart 3D-MRI for cardiac morphology allows reliable discrimination between normal and abnormal coronary anatomy in children/adolescents with CHD. Purpose: To determine the value of whole-heart three-dimensional magnetic resonance imaging (MRI) for coronary artery imaging in children/adolescents with congenital heart disease (CHD). Materials and Methods: Forty children/adolescents (median age: 14 years, range 2.6-25.8) with CHD underwent free-breathing navigator-gated isotropic three-dimensional steady-state free-precession (3D-SSFP) MRI for cardiac morphology. Two observers independently evaluated visibility of origin, course, vessel lengths, image quality (IQ), and contrast between coronary lumen and myocardium. A subgroup was compared with cardiac catheter. Results: The total scan time was 6.3 ± 3.2 minutes (mean ± SD, at mean heart rate 76 ± 15/min). The mean vessel length for right coronary artery (RCA) by observer 1 was 97 ± 43 mm (observer 2: 94 ± 37 mm), for left main and anterior descending artery (LM/LAD) 91 ± 40 mm (observer 2: 90 ± 40 mm), and for left circumflex artery (LCX) 64 ± 28mm (observer 2: 66 ± 28 mm). The mean vessel contrast was 0.34 ± 0.05 (range: 0.23-0.45; maximum = 1, minimum = 0). On a 4-level score (1 = nondiagnostic, 4 = excellent), mean IQ scores ranged between 2.3-2.9 (±0.8-1.0). Both observers agreed on the presence/proximal course of RCA in 40/40, LM/LAD in 38/40, and LCX in 36/40 patients. There was complete agreement with invasive coronary angiography available in 12/40 patients (six anomalies).

Original languageEnglish (US)
Pages (from-to)320-327
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Volume29
Issue number2
DOIs
StatePublished - Feb 1 2009

Keywords

  • Angiography
  • Congenital heart disease
  • Coronary arteries
  • Magnetic resonance imaging
  • Pediatrics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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