Correlation of hepatic vein doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease

Amir Reza Mohammadinia, Khadijeh Bakhtavar, Nasser Ebrahimi-Daryani, Peiman Habibollahi, Mohammad Reza Keramati, Seyed Mohammad Fereshtehnejad, Sina Abdollahzade

Research output: Contribution to journalArticle

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Abstract

Purpose. The study was conducted to evaluate the effect of various degrees of fatty infiltration in patients with nonalcoholic fatty liver disease on hepatic artery resistance index and hepatic vein waveform patterns. Methods. After identification and grading of fatty infiltration, 60 patients and 20 normal healthy subjects were examined using color and spectral Doppler sonography. The level of fatty liver infiltration was ascertained and graded by biopsy in patients and excluded by MRI in controls. The patients were allocated to four study groups consecutively, until the required number was reached, according to infiltration level as follows: normal (group A), mild (group B), moderate (group C), and severe (group D). The hepatic vein waveforms were classified into the three following groups: triphasic, biphasic, and monophasic waveform. The hepatic artery resistance index was calculated as the mean of three different measurements. Results. The incidence of monophasic and biphasic hepatic vein waveform was 2 (10%) for group B, 11 (55%) for group C, 16 (80%) for group D, and none for group A. The difference in the distribution of triphasic Doppler waveform pattern between the patients and the control group was significant (p < 0.001). Hepatic artery resistance index was 0.81 (60.02), 0.78 (60.03), 0.73 (60.03), and 0.68 (60.05), respectively, in groups A, B, C, and D and was significantly different between groups (p < 0.001).Conclusion. As the severity of nonalcoholic fatty infiltration increases, the incidence of abnormal hepatic vein waveforms increases and hepatic artery resistance index decreases.

Original languageEnglish (US)
Pages (from-to)346-352
Number of pages7
JournalJournal of Clinical Ultrasound
Volume38
Issue number7
DOIs
StatePublished - Sep 1 2010
Externally publishedYes

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Hepatic Veins
Hepatic Artery
Doppler Color Ultrasonography
Incidence
Fatty Liver
Healthy Volunteers
Non-alcoholic Fatty Liver Disease
Biopsy
Control Groups

Keywords

  • Hepatic artery resistance index
  • Hepatic vein waveform
  • Nonalcoholic fatty liver disease

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Mohammadinia, A. R., Bakhtavar, K., Ebrahimi-Daryani, N., Habibollahi, P., Keramati, M. R., Fereshtehnejad, S. M., & Abdollahzade, S. (2010). Correlation of hepatic vein doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease. Journal of Clinical Ultrasound, 38(7), 346-352. https://doi.org/10.1002/jcu.20696

Correlation of hepatic vein doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease. / Mohammadinia, Amir Reza; Bakhtavar, Khadijeh; Ebrahimi-Daryani, Nasser; Habibollahi, Peiman; Keramati, Mohammad Reza; Fereshtehnejad, Seyed Mohammad; Abdollahzade, Sina.

In: Journal of Clinical Ultrasound, Vol. 38, No. 7, 01.09.2010, p. 346-352.

Research output: Contribution to journalArticle

Mohammadinia, AR, Bakhtavar, K, Ebrahimi-Daryani, N, Habibollahi, P, Keramati, MR, Fereshtehnejad, SM & Abdollahzade, S 2010, 'Correlation of hepatic vein doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease', Journal of Clinical Ultrasound, vol. 38, no. 7, pp. 346-352. https://doi.org/10.1002/jcu.20696
Mohammadinia, Amir Reza ; Bakhtavar, Khadijeh ; Ebrahimi-Daryani, Nasser ; Habibollahi, Peiman ; Keramati, Mohammad Reza ; Fereshtehnejad, Seyed Mohammad ; Abdollahzade, Sina. / Correlation of hepatic vein doppler waveform and hepatic artery resistance index with the severity of nonalcoholic fatty liver disease. In: Journal of Clinical Ultrasound. 2010 ; Vol. 38, No. 7. pp. 346-352.
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abstract = "Purpose. The study was conducted to evaluate the effect of various degrees of fatty infiltration in patients with nonalcoholic fatty liver disease on hepatic artery resistance index and hepatic vein waveform patterns. Methods. After identification and grading of fatty infiltration, 60 patients and 20 normal healthy subjects were examined using color and spectral Doppler sonography. The level of fatty liver infiltration was ascertained and graded by biopsy in patients and excluded by MRI in controls. The patients were allocated to four study groups consecutively, until the required number was reached, according to infiltration level as follows: normal (group A), mild (group B), moderate (group C), and severe (group D). The hepatic vein waveforms were classified into the three following groups: triphasic, biphasic, and monophasic waveform. The hepatic artery resistance index was calculated as the mean of three different measurements. Results. The incidence of monophasic and biphasic hepatic vein waveform was 2 (10{\%}) for group B, 11 (55{\%}) for group C, 16 (80{\%}) for group D, and none for group A. The difference in the distribution of triphasic Doppler waveform pattern between the patients and the control group was significant (p < 0.001). Hepatic artery resistance index was 0.81 (60.02), 0.78 (60.03), 0.73 (60.03), and 0.68 (60.05), respectively, in groups A, B, C, and D and was significantly different between groups (p < 0.001).Conclusion. As the severity of nonalcoholic fatty infiltration increases, the incidence of abnormal hepatic vein waveforms increases and hepatic artery resistance index decreases.",
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AU - Mohammadinia, Amir Reza

AU - Bakhtavar, Khadijeh

AU - Ebrahimi-Daryani, Nasser

AU - Habibollahi, Peiman

AU - Keramati, Mohammad Reza

AU - Fereshtehnejad, Seyed Mohammad

AU - Abdollahzade, Sina

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N2 - Purpose. The study was conducted to evaluate the effect of various degrees of fatty infiltration in patients with nonalcoholic fatty liver disease on hepatic artery resistance index and hepatic vein waveform patterns. Methods. After identification and grading of fatty infiltration, 60 patients and 20 normal healthy subjects were examined using color and spectral Doppler sonography. The level of fatty liver infiltration was ascertained and graded by biopsy in patients and excluded by MRI in controls. The patients were allocated to four study groups consecutively, until the required number was reached, according to infiltration level as follows: normal (group A), mild (group B), moderate (group C), and severe (group D). The hepatic vein waveforms were classified into the three following groups: triphasic, biphasic, and monophasic waveform. The hepatic artery resistance index was calculated as the mean of three different measurements. Results. The incidence of monophasic and biphasic hepatic vein waveform was 2 (10%) for group B, 11 (55%) for group C, 16 (80%) for group D, and none for group A. The difference in the distribution of triphasic Doppler waveform pattern between the patients and the control group was significant (p < 0.001). Hepatic artery resistance index was 0.81 (60.02), 0.78 (60.03), 0.73 (60.03), and 0.68 (60.05), respectively, in groups A, B, C, and D and was significantly different between groups (p < 0.001).Conclusion. As the severity of nonalcoholic fatty infiltration increases, the incidence of abnormal hepatic vein waveforms increases and hepatic artery resistance index decreases.

AB - Purpose. The study was conducted to evaluate the effect of various degrees of fatty infiltration in patients with nonalcoholic fatty liver disease on hepatic artery resistance index and hepatic vein waveform patterns. Methods. After identification and grading of fatty infiltration, 60 patients and 20 normal healthy subjects were examined using color and spectral Doppler sonography. The level of fatty liver infiltration was ascertained and graded by biopsy in patients and excluded by MRI in controls. The patients were allocated to four study groups consecutively, until the required number was reached, according to infiltration level as follows: normal (group A), mild (group B), moderate (group C), and severe (group D). The hepatic vein waveforms were classified into the three following groups: triphasic, biphasic, and monophasic waveform. The hepatic artery resistance index was calculated as the mean of three different measurements. Results. The incidence of monophasic and biphasic hepatic vein waveform was 2 (10%) for group B, 11 (55%) for group C, 16 (80%) for group D, and none for group A. The difference in the distribution of triphasic Doppler waveform pattern between the patients and the control group was significant (p < 0.001). Hepatic artery resistance index was 0.81 (60.02), 0.78 (60.03), 0.73 (60.03), and 0.68 (60.05), respectively, in groups A, B, C, and D and was significantly different between groups (p < 0.001).Conclusion. As the severity of nonalcoholic fatty infiltration increases, the incidence of abnormal hepatic vein waveforms increases and hepatic artery resistance index decreases.

KW - Hepatic artery resistance index

KW - Hepatic vein waveform

KW - Nonalcoholic fatty liver disease

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