Correlation of West Nile virus incidence in donated blood with West Nile neuroinvasive disease rates, United States, 2010–2012

Edouard Betsem, Zhanna Kaidarova, Susan L. Stramer, Beth Shaz, Merlyn Sayers, German LeParc, Brian Custer, Michael P. Busch, Edward L. Murphy

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Over the past decade, West Nile virus (WNV) has spread across the United States. We aggregated blood donor data from 2010-2012 and then calculated the incidence of WNV RNA-positive donations and compared the incidence with neuroinvasive disease (NID) case data from the ArboNET surveillance system. Of 10,107,853 donations, 640 were confirmed positive. The seasonal WNV incidence rate per 100,000 persons was 33.4 (95% CI 22-45) in 2010, 25.7 (95% CI 15-34) in 2011, and 119.9 (95% CI 98-141) in 2012. NID to blood donor ratios were 1 in 164 (95% CI 152-178) in 2010, 1 in 158 (95% CI 145-174) in 2011, and 1 in 131 (95% CI 127-136) in 2012. We updated estimates of the ratio of NID to WNV infection rates, demonstrating stable disease penetrance over the study period. Blood donor WNV RNA screening is a valuable public health tool for WNV surveillance.

Original languageEnglish (US)
Pages (from-to)212-219
Number of pages8
JournalEmerging Infectious Diseases
Volume23
Issue number2
DOIs
StatePublished - Feb 1 2017

Fingerprint

West Nile virus
Incidence
Blood Donors
RNA
Penetrance
Virus Diseases
Public Health

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Correlation of West Nile virus incidence in donated blood with West Nile neuroinvasive disease rates, United States, 2010–2012. / Betsem, Edouard; Kaidarova, Zhanna; Stramer, Susan L.; Shaz, Beth; Sayers, Merlyn; LeParc, German; Custer, Brian; Busch, Michael P.; Murphy, Edward L.

In: Emerging Infectious Diseases, Vol. 23, No. 2, 01.02.2017, p. 212-219.

Research output: Contribution to journalArticle

Betsem, Edouard ; Kaidarova, Zhanna ; Stramer, Susan L. ; Shaz, Beth ; Sayers, Merlyn ; LeParc, German ; Custer, Brian ; Busch, Michael P. ; Murphy, Edward L. / Correlation of West Nile virus incidence in donated blood with West Nile neuroinvasive disease rates, United States, 2010–2012. In: Emerging Infectious Diseases. 2017 ; Vol. 23, No. 2. pp. 212-219.
@article{2d2b034f375e4bd0bc261709489a0463,
title = "Correlation of West Nile virus incidence in donated blood with West Nile neuroinvasive disease rates, United States, 2010–2012",
abstract = "Over the past decade, West Nile virus (WNV) has spread across the United States. We aggregated blood donor data from 2010-2012 and then calculated the incidence of WNV RNA-positive donations and compared the incidence with neuroinvasive disease (NID) case data from the ArboNET surveillance system. Of 10,107,853 donations, 640 were confirmed positive. The seasonal WNV incidence rate per 100,000 persons was 33.4 (95{\%} CI 22-45) in 2010, 25.7 (95{\%} CI 15-34) in 2011, and 119.9 (95{\%} CI 98-141) in 2012. NID to blood donor ratios were 1 in 164 (95{\%} CI 152-178) in 2010, 1 in 158 (95{\%} CI 145-174) in 2011, and 1 in 131 (95{\%} CI 127-136) in 2012. We updated estimates of the ratio of NID to WNV infection rates, demonstrating stable disease penetrance over the study period. Blood donor WNV RNA screening is a valuable public health tool for WNV surveillance.",
author = "Edouard Betsem and Zhanna Kaidarova and Stramer, {Susan L.} and Beth Shaz and Merlyn Sayers and German LeParc and Brian Custer and Busch, {Michael P.} and Murphy, {Edward L.}",
year = "2017",
month = "2",
day = "1",
doi = "10.3201/eid2302.161058",
language = "English (US)",
volume = "23",
pages = "212--219",
journal = "Emerging Infectious Diseases",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "2",

}

TY - JOUR

T1 - Correlation of West Nile virus incidence in donated blood with West Nile neuroinvasive disease rates, United States, 2010–2012

AU - Betsem, Edouard

AU - Kaidarova, Zhanna

AU - Stramer, Susan L.

AU - Shaz, Beth

AU - Sayers, Merlyn

AU - LeParc, German

AU - Custer, Brian

AU - Busch, Michael P.

AU - Murphy, Edward L.

PY - 2017/2/1

Y1 - 2017/2/1

N2 - Over the past decade, West Nile virus (WNV) has spread across the United States. We aggregated blood donor data from 2010-2012 and then calculated the incidence of WNV RNA-positive donations and compared the incidence with neuroinvasive disease (NID) case data from the ArboNET surveillance system. Of 10,107,853 donations, 640 were confirmed positive. The seasonal WNV incidence rate per 100,000 persons was 33.4 (95% CI 22-45) in 2010, 25.7 (95% CI 15-34) in 2011, and 119.9 (95% CI 98-141) in 2012. NID to blood donor ratios were 1 in 164 (95% CI 152-178) in 2010, 1 in 158 (95% CI 145-174) in 2011, and 1 in 131 (95% CI 127-136) in 2012. We updated estimates of the ratio of NID to WNV infection rates, demonstrating stable disease penetrance over the study period. Blood donor WNV RNA screening is a valuable public health tool for WNV surveillance.

AB - Over the past decade, West Nile virus (WNV) has spread across the United States. We aggregated blood donor data from 2010-2012 and then calculated the incidence of WNV RNA-positive donations and compared the incidence with neuroinvasive disease (NID) case data from the ArboNET surveillance system. Of 10,107,853 donations, 640 were confirmed positive. The seasonal WNV incidence rate per 100,000 persons was 33.4 (95% CI 22-45) in 2010, 25.7 (95% CI 15-34) in 2011, and 119.9 (95% CI 98-141) in 2012. NID to blood donor ratios were 1 in 164 (95% CI 152-178) in 2010, 1 in 158 (95% CI 145-174) in 2011, and 1 in 131 (95% CI 127-136) in 2012. We updated estimates of the ratio of NID to WNV infection rates, demonstrating stable disease penetrance over the study period. Blood donor WNV RNA screening is a valuable public health tool for WNV surveillance.

UR - http://www.scopus.com/inward/record.url?scp=85009997105&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85009997105&partnerID=8YFLogxK

U2 - 10.3201/eid2302.161058

DO - 10.3201/eid2302.161058

M3 - Article

VL - 23

SP - 212

EP - 219

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 2

ER -