Cortical activity patterns predict speech discrimination ability

Crystal T. Engineer, Claudia A. Perez, Ye Ting H. Chen, Ryan S. Carraway, Amanda C. Reed, Jai A. Shetake, Vikram Jakkamsetti, Kevin Q. Chang, Michael P. Kilgard

Research output: Contribution to journalArticle

138 Citations (Scopus)

Abstract

Neural activity in the cerebral cortex can explain many aspects of sensory perception. Extensive psychophysical and neurophysiological studies of visual motion and vibrotactile processing show that the firing rate of cortical neurons averaged across 50-500 ms is well correlated with discrimination ability. In this study, we tested the hypothesis that primary auditory cortex (A1) neurons use temporal precision on the order of 1-10 ms to represent speech sounds shifted into the rat hearing range. Neural discrimination was highly correlated with behavioral performance on 11 consonant-discrimination tasks when spike timing was preserved and was not correlated when spike timing was eliminated. This result suggests that spike timing contributes to the auditory cortex representation of consonant sounds.

Original languageEnglish (US)
Pages (from-to)603-608
Number of pages6
JournalNature Neuroscience
Volume11
Issue number5
DOIs
StatePublished - May 29 2008

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Speech Perception
Aptitude
Auditory Cortex
Neurons
Phonetics
Cerebral Cortex
Hearing
Discrimination (Psychology)

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Engineer, C. T., Perez, C. A., Chen, Y. T. H., Carraway, R. S., Reed, A. C., Shetake, J. A., ... Kilgard, M. P. (2008). Cortical activity patterns predict speech discrimination ability. Nature Neuroscience, 11(5), 603-608. https://doi.org/10.1038/nn.2109

Cortical activity patterns predict speech discrimination ability. / Engineer, Crystal T.; Perez, Claudia A.; Chen, Ye Ting H.; Carraway, Ryan S.; Reed, Amanda C.; Shetake, Jai A.; Jakkamsetti, Vikram; Chang, Kevin Q.; Kilgard, Michael P.

In: Nature Neuroscience, Vol. 11, No. 5, 29.05.2008, p. 603-608.

Research output: Contribution to journalArticle

Engineer, CT, Perez, CA, Chen, YTH, Carraway, RS, Reed, AC, Shetake, JA, Jakkamsetti, V, Chang, KQ & Kilgard, MP 2008, 'Cortical activity patterns predict speech discrimination ability', Nature Neuroscience, vol. 11, no. 5, pp. 603-608. https://doi.org/10.1038/nn.2109
Engineer CT, Perez CA, Chen YTH, Carraway RS, Reed AC, Shetake JA et al. Cortical activity patterns predict speech discrimination ability. Nature Neuroscience. 2008 May 29;11(5):603-608. https://doi.org/10.1038/nn.2109
Engineer, Crystal T. ; Perez, Claudia A. ; Chen, Ye Ting H. ; Carraway, Ryan S. ; Reed, Amanda C. ; Shetake, Jai A. ; Jakkamsetti, Vikram ; Chang, Kevin Q. ; Kilgard, Michael P. / Cortical activity patterns predict speech discrimination ability. In: Nature Neuroscience. 2008 ; Vol. 11, No. 5. pp. 603-608.
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