Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping

Scott McHenry, Yeshika Sharma, Ankita Tirath, Richard Tsai, Aaron Mintz, Tyler J. Fraum, Amber Salter, Jeffrey D. Browning, Avegail G. Flores, Nicholas O. Davidson, Kathryn J. Fowler, Matthew A. Ciorba, Parakkal Deepak

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations

Abstract

Nonalcoholic fatty liver disease (NAFLD) commonly coexists with Crohn's disease (CD); however, it remains unclear if it is more prevalent than would be expected as ultrasound surveys of CD patients report a very wide range of prevalence (9%–40%).1–3 To address this uncertainty, we performed a prospective, cross-sectional survey of NAFLD in CD patients by generating magnetic resonance proton density fat fraction (MR-PDFF) maps as compared with 2 control populations. MR-PDFF provides a quantitative, sensitive and specific (97% and 100%, respectively) radiographic surrogate for liver fat.4

Original languageEnglish (US)
Pages (from-to)2816-2818
Number of pages3
JournalClinical Gastroenterology and Hepatology
Volume17
Issue number13
DOIs
StatePublished - Dec 2019

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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