Current evidence-based opinions in the management of adenocarcionoma of the rectum

Sergio Huerta, Bryce Murray, Craig Olson, Prapti Patel, Thomas Anthony

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

The management of rectal cancer has drastically evolved over the past two decades as a result of implementation of circular stapling devices and the introduction of neoadjuvant chemoradiation. In spite of current aggressive multimodality treatments, the recurrence rate remains unacceptably high and the expected 5-year survival in patients who develop recurrent disease is dismal. The management of rectal cancer must involve a multidisciplinary approach. An understanding of the biology of rectal tumours may allow for selection of patients who may have an aggressive phenotype allowing for alterations in the operative and neoadjuvant planning. Efforts to improve local control and survival in rectal cancer are the focus of multiple current clinical and preclinical research efforts. Preoperative chemoradiation for and surgical management of rectal cancer, including the laparoscopic approach are areas of dynamic progression. In the present report, we review the current evidence in the new strategies pertaining to the multimodality approach in the management of rectal cancer.

Original languageEnglish (US)
Pages (from-to)356-362
Number of pages7
JournalIndian Journal of Surgery
Volume71
Issue number6
DOIs
StatePublished - Dec 1 2009

Keywords

  • Endorectal ultrasound
  • Induction chemotherapy
  • Laparoscopic LAR
  • Preoperative staging
  • Rectum

ASJC Scopus subject areas

  • Surgery

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