Current progress of aptamer-based molecular imaging

Andrew Z. Wang, Omid C. Farokhzad

Research output: Contribution to journalReview articlepeer-review

76 Scopus citations

Abstract

Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligand. Since their discovery, aptamers have been rapidly translated into clinical practice. They have been approved as therapeutics and molecular diagnostics. Aptamers also possess several properties that make them uniquely suited to molecular imaging. This review aims to provide an overview of aptamers' advantages as targeting ligands and their application in molecular imaging.

Original languageEnglish (US)
Pages (from-to)353-356
Number of pages4
JournalJournal of Nuclear Medicine
Volume55
Issue number3
DOIs
StatePublished - Mar 1 2014
Externally publishedYes

Keywords

  • Aptamer
  • Aptamers
  • Molecular diagnostics
  • Molecular imaging probes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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