Danazol therapy in immune thrombocytopenic purpura

R. K. Marwaha, R. P. Singh, G. Garewal, N. Marwaha, D. Prakash, R. Sarode

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Nine children with chronic refractory immune thrombocytopenic purpura and moderate to severe episodes of bleeding were treated with Danazol in an attempt to increase their platelet counts and improve clinical hemostasis. Only one patient experienced an excellent response while a good response was obtained in another. Cessation of bleeding episodes was observed in two other children with only marginal increases in platelet counts. Four of the nine patients failed to show any clinical or hematological improvement. The drug was well tolerated but its efficacy in childhood ITP needs further evaluation.

Original languageEnglish (US)
Pages (from-to)193-198
Number of pages6
JournalPediatric Hematology and Oncology
Volume7
Issue number2
DOIs
StatePublished - 1990

Fingerprint

Danazol
Idiopathic Thrombocytopenic Purpura
Platelets
Platelet Count
Hemorrhage
Inosine Triphosphate
Hemostasis
Refractory materials
Therapeutics
Pharmaceutical Preparations
Therapy
Efficacy
Evaluation
Drugs
Childhood

Keywords

  • Danazol
  • Immune thrombocytopenic purpura

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology
  • Cancer Research
  • Management of Technology and Innovation

Cite this

Marwaha, R. K., Singh, R. P., Garewal, G., Marwaha, N., Prakash, D., & Sarode, R. (1990). Danazol therapy in immune thrombocytopenic purpura. Pediatric Hematology and Oncology, 7(2), 193-198. https://doi.org/10.3109/08880019009033391

Danazol therapy in immune thrombocytopenic purpura. / Marwaha, R. K.; Singh, R. P.; Garewal, G.; Marwaha, N.; Prakash, D.; Sarode, R.

In: Pediatric Hematology and Oncology, Vol. 7, No. 2, 1990, p. 193-198.

Research output: Contribution to journalArticle

Marwaha, RK, Singh, RP, Garewal, G, Marwaha, N, Prakash, D & Sarode, R 1990, 'Danazol therapy in immune thrombocytopenic purpura', Pediatric Hematology and Oncology, vol. 7, no. 2, pp. 193-198. https://doi.org/10.3109/08880019009033391
Marwaha, R. K. ; Singh, R. P. ; Garewal, G. ; Marwaha, N. ; Prakash, D. ; Sarode, R. / Danazol therapy in immune thrombocytopenic purpura. In: Pediatric Hematology and Oncology. 1990 ; Vol. 7, No. 2. pp. 193-198.
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