Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue

Oliwia Rysnik; Kirsty McHugh; Leonie van Duivenvoorde; Melissa van Tok; Joel Taurog; Simon Kollnberger; Dominique Baeten; Paul Bowness

doi:10.1016/j.dib.2016.08.046

Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue

Oliwia Rysnik, Kirsty McHugh, Leonie van Duivenvoorde, Melissa van Tok, Joel Taurog, Simon Kollnberger, Dominique Baeten, Paul Bowness

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Data is presented showing expression of non-conventional (NC) heavy chain forms of B27 in synovial tissues from SpA patients. Data is presented showing the expression patterns of NC-B27 in joint, gastrointestinal and lymphoid tissues from B27 transgenic (TG¹) rats with M. tuberculosis-induced SpA. Expression of NC-B27 was determined by immunohistochemistry and flow cytometry using HC10 and HD6 antibodies. These data are the extension of the data presented and discussed in “Non-conventional forms of HLA-B27 are expressed in Spondyloarthritis joints and gut tissue” (O. Rysnik, K. McHugh, L. M. van Duivenvoorde, M. N. van Tok, G. Guggino, J. D. Taurog, S. Kollnberger, F. Ciccia, D. L. Baeten, P. Bowness, 2016) [1].

Original language	English (US)
Pages (from-to)	100-111
Number of pages	12
Journal	Data in Brief
Volume	9
DOIs	https://doi.org/10.1016/j.dib.2016.08.046
State	Published - Dec 2016

Keywords

HLA class I free-heavy chains
HLA-B27
HLA-B27 transgenic rat model
Spondyloarthropathies

ASJC Scopus subject areas

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10.1016/j.dib.2016.08.046

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@article{721fd416b7874ed0a8f875f62d6c1177,

title = "Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue",

abstract = "Data is presented showing expression of non-conventional (NC) heavy chain forms of B27 in synovial tissues from SpA patients. Data is presented showing the expression patterns of NC-B27 in joint, gastrointestinal and lymphoid tissues from B27 transgenic (TG1) rats with M. tuberculosis-induced SpA. Expression of NC-B27 was determined by immunohistochemistry and flow cytometry using HC10 and HD6 antibodies. These data are the extension of the data presented and discussed in “Non-conventional forms of HLA-B27 are expressed in Spondyloarthritis joints and gut tissue” (O. Rysnik, K. McHugh, L. M. van Duivenvoorde, M. N. van Tok, G. Guggino, J. D. Taurog, S. Kollnberger, F. Ciccia, D. L. Baeten, P. Bowness, 2016) [1].",

keywords = "HLA class I free-heavy chains, HLA-B27, HLA-B27 transgenic rat model, Spondyloarthropathies",

author = "Oliwia Rysnik and Kirsty McHugh and {van Duivenvoorde}, Leonie and {van Tok}, Melissa and Joel Taurog and Simon Kollnberger and Dominique Baeten and Paul Bowness",

note = "Publisher Copyright: {\textcopyright} 2016",

year = "2016",

month = dec,

doi = "10.1016/j.dib.2016.08.046",

language = "English (US)",

volume = "9",

pages = "100--111",

journal = "Data in Brief",

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T1 - Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue

AU - Rysnik, Oliwia

AU - McHugh, Kirsty

AU - van Duivenvoorde, Leonie

AU - van Tok, Melissa

AU - Taurog, Joel

AU - Kollnberger, Simon

AU - Baeten, Dominique

AU - Bowness, Paul

PY - 2016/12

Y1 - 2016/12

N2 - Data is presented showing expression of non-conventional (NC) heavy chain forms of B27 in synovial tissues from SpA patients. Data is presented showing the expression patterns of NC-B27 in joint, gastrointestinal and lymphoid tissues from B27 transgenic (TG1) rats with M. tuberculosis-induced SpA. Expression of NC-B27 was determined by immunohistochemistry and flow cytometry using HC10 and HD6 antibodies. These data are the extension of the data presented and discussed in “Non-conventional forms of HLA-B27 are expressed in Spondyloarthritis joints and gut tissue” (O. Rysnik, K. McHugh, L. M. van Duivenvoorde, M. N. van Tok, G. Guggino, J. D. Taurog, S. Kollnberger, F. Ciccia, D. L. Baeten, P. Bowness, 2016) [1].

AB - Data is presented showing expression of non-conventional (NC) heavy chain forms of B27 in synovial tissues from SpA patients. Data is presented showing the expression patterns of NC-B27 in joint, gastrointestinal and lymphoid tissues from B27 transgenic (TG1) rats with M. tuberculosis-induced SpA. Expression of NC-B27 was determined by immunohistochemistry and flow cytometry using HC10 and HD6 antibodies. These data are the extension of the data presented and discussed in “Non-conventional forms of HLA-B27 are expressed in Spondyloarthritis joints and gut tissue” (O. Rysnik, K. McHugh, L. M. van Duivenvoorde, M. N. van Tok, G. Guggino, J. D. Taurog, S. Kollnberger, F. Ciccia, D. L. Baeten, P. Bowness, 2016) [1].

KW - HLA class I free-heavy chains

KW - HLA-B27

KW - HLA-B27 transgenic rat model

KW - Spondyloarthropathies

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DO - 10.1016/j.dib.2016.08.046

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C2 - 27642616

AN - SCOPUS:85030263297

SN - 2352-3409

VL - 9

SP - 100

EP - 111

JO - Data in Brief

JF - Data in Brief

ER -

Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue

Abstract

Keywords

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