De novo autoimmune hepatitis during immune reconstitution in an HIV-infected patient receiving highly active antiretroviral therapy

Jacqueline G. O'Leary, Kimon Zachary, Joseph Misdraji, Raymond T. Chung

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33 Scopus citations

Abstract

Immune reconstitution inflammatory syndrome is typically seen in human immunodeficiency virus-seropositive patients who commence antiretroviral therapy. In patients who experience this syndrome, the immune system's reconstitution leads to a response directed against pathogens or autoantigens. We report, to our knowledge, the first case of autoimmune hepatitis caused by immune reconstitution.

Original languageEnglish (US)
JournalClinical Infectious Diseases
Volume46
Issue number1
DOIs
Publication statusPublished - Jan 1 2008

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ASJC Scopus subject areas

  • Immunology

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