Determining the longitudinal relaxation time (T1) of blood at 3.0 tesla

Hanzhang Lu, Chekesha Clingman, Xavier Golay, Peter C M Van Zijl

Research output: Contribution to journalArticle

455 Scopus citations

Abstract

It is important to determine the longitudinal relaxation time of blood for black blood imaging, as well as for quantifying blood flow by arterial spin labeling (ASL). In this study a circulation system was used to measure blood T1 under physiological conditions at the new clinical field strength of 3.0T. It was found thet 1/T1 in s-1 was linearly dependent (P < 0.05) on hemetocrit (Hct) within a normal range of 0.38-0.46. The relationships were 1/T1 = (0.52 ± 0.15) · Hct + (0.38 ± 0.06) and 1/T1 = (0.83 ± 0.07) · Hct + (0.28 ± 0.03) for arterial (oxygenation = 92% ± 7%) and venous blood (69% ± 8%), respectively, which led to estimated T1 values of 1664 ± 14 ms (arterial) and 1584 ± 5 ms (venous) at a typical human Hct of 0.42. The temperature dependencies of blood T1 were 22.3 ± 0.6 ms/°C and 19.8 ± 0.8 ms/°C for Hct values of 0.42 and 0.38, respectively. When a head coil transmit/receive setup was used, radiation damping caused a slight reduction (19 ms) of the measured T 1 values.

Original languageEnglish (US)
Pages (from-to)679-682
Number of pages4
JournalMagnetic resonance in medicine
Volume52
Issue number3
DOIs
StatePublished - Sep 2004

Keywords

  • 3 Tesla
  • Blood
  • Hematocrit
  • Longitudinal relaxation
  • Radiation damping
  • T

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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