@article{139f4dd6793345e1899556101c387f97,
title = "Detrimental effects of specific Periodontopathic bacterial infection on tachyarrhythmia compared to Bradyarrhythmia",
abstract = "Background: Tachyarrhythmia (TA) and bradyarrhythmia (BA) are cardiac rhythm disorders that result in the decline of quality of life. While patients with periodontitis are at a high risk of cardiovascular disease (CVD), little causal information between TA and BA has been provided to date. To assess the relationship, periodontal bacterial infection in patients with TA or BA was evaluated. Methods: The subjects were patients with TA (n = 98) or BA (n = 40) who attended Tokyo Medical and Dental University hospital. Periodontal and blood examinations were performed. Periodontopathic bacterial existence in saliva was evaluated. Results: We found that specific periodontopathic bacteria, Porphyromonas gingivalis and Prevotella intermedia, were highly detected in saliva from TA patients compared to BA subjects. The rates of hypertension and dyslipidemia were comparable between the two groups. Conclusion: Specific periodontal bacterial infection might affect TA progression.",
keywords = "Arrhythmia, Bacteria, Periodontal disease",
author = "Norio Aoyama and Suzuki, {Jun ichi} and Naho Kobayashi and Tomoya Hanatani and Norihiko Ashigaki and Asuka Yoshida and Yuka Shiheido and Hiroki Sato and Hidetoshi Kumagai and Yuichi Ikeda and Hiroshi Akazawa and Issei Komuro and Masato Minabe and Yuichi Izumi and Mitsuaki Isobe",
note = "Funding Information: This work was supported by JSPS KAKENHI Grant Numbers (JP25870198, JP15K20616, and JP16H05824), Ministry of Education, Culture, Sports, Science and Technology of Japan, Mitsui Life Insurance Research Foundation, Mitsui Sumitomo Marine Welfare Research Foundation, Geriatric Dental Research Foundation, Human Health Future Research Foundation, St. Luke{\textquoteright}s Hospital Research Foundation, Health Management Foundation, Taiyo Life Insurance Research Foundation, The 8020 Promotion Foundation, Terumo Science Foundation, Pfizer Health Research Foundation, General Health Promotion Foundation, Suzuken Memorial Foundation, Health Science Center Foundation, Kobayashi International Scholarship Foundation, Banyu Life Science Foundation International, and Hakujikai Institute of Gerontology Foundation. Publisher Copyright: {\textcopyright} 2017 The Author(s).",
year = "2017",
month = oct,
day = "17",
doi = "10.1186/s12872-017-0703-2",
language = "English (US)",
volume = "17",
journal = "BMC Cardiovascular Disorders",
issn = "1471-2261",
publisher = "BioMed Central",
number = "1",
}