Detrimental effects of specific Periodontopathic bacterial infection on tachyarrhythmia compared to Bradyarrhythmia

Norio Aoyama, Jun ichi Suzuki, Naho Kobayashi, Tomoya Hanatani, Norihiko Ashigaki, Asuka Yoshida, Yuka Shiheido, Hiroki Sato, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Issei Komuro, Masato Minabe, Yuichi Izumi, Mitsuaki Isobe

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: Tachyarrhythmia (TA) and bradyarrhythmia (BA) are cardiac rhythm disorders that result in the decline of quality of life. While patients with periodontitis are at a high risk of cardiovascular disease (CVD), little causal information between TA and BA has been provided to date. To assess the relationship, periodontal bacterial infection in patients with TA or BA was evaluated. Methods: The subjects were patients with TA (n = 98) or BA (n = 40) who attended Tokyo Medical and Dental University hospital. Periodontal and blood examinations were performed. Periodontopathic bacterial existence in saliva was evaluated. Results: We found that specific periodontopathic bacteria, Porphyromonas gingivalis and Prevotella intermedia, were highly detected in saliva from TA patients compared to BA subjects. The rates of hypertension and dyslipidemia were comparable between the two groups. Conclusion: Specific periodontal bacterial infection might affect TA progression.

Original languageEnglish (US)
Article number267
JournalBMC Cardiovascular Disorders
Volume17
Issue number1
DOIs
StatePublished - Oct 17 2017

Keywords

  • Arrhythmia
  • Bacteria
  • Periodontal disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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