Developmental changes in the degradation of thyrotrophin releasing hormone by the serum and brain tissues of the male rat

C. Oliver, C. R. Parker, J. C. Porter

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

These results show a dissociation between the abilities of serum and brain homogenates to degrade synthetic TRH. In young rats, the inactivation rate of TRH is low in serum, but high in the brain, and after day 14 of life, TRH degrading activity in the serum increases whereas that in the brain decreases. The physiological role of these age-related changes in the degradation of TRH remains to be established.

Original languageEnglish (US)
Pages (from-to)339-340
Number of pages2
JournalJournal of Endocrinology
Volume74
Issue number2
DOIs
StatePublished - 1977

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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