Diagnostic Accuracy of Probe to Bone to Detect Osteomyelitis in the Diabetic Foot: A Systematic Review

Kenrick Lam, Suzanne A V Van Asten, Tea Nguyen, Javier La Fontaine, Lawrence A. Lavery

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

The probe-to-bone (PTB) test is a commonly used clinical test for osteomyelitis (OM), but its utility has been questioned in clinical settings where the prevalence of OM is low. This article aims to systematically review the accuracy of the PTB test to diagnose diabetic foot OM. We searched Ovid Medline and Scopus databases for studies using the keywords "probe to bone," "osteomyelitis," and "diabetic foot" from 1946 to May 2015. We summarized characteristics of the included studies and pooled the accuracy numbers using a bivariate random-effects model. Seven studies met our inclusion criteria. Pooled sensitivity and specificity for the PTB test was 0.87 (95% confidence interval [CI],. 75-.93) and 0.83 (95% CI,. 65-.93), respectively. We conclude that the PTB test can accurately rule in diabetic foot OM in the high-risk patients and rule out OM in low-risk patients.

Original languageEnglish (US)
Pages (from-to)944-948
Number of pages5
JournalClinical Infectious Diseases
Volume63
Issue number7
DOIs
StatePublished - Oct 1 2016

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Diabetic Foot
Osteomyelitis
Bone and Bones
Confidence Intervals
Databases
Sensitivity and Specificity

Keywords

  • accuracy
  • diabetic foot
  • meta-analysis
  • osteomyelitis
  • probe to bone

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Diagnostic Accuracy of Probe to Bone to Detect Osteomyelitis in the Diabetic Foot : A Systematic Review. / Lam, Kenrick; Van Asten, Suzanne A V; Nguyen, Tea; La Fontaine, Javier; Lavery, Lawrence A.

In: Clinical Infectious Diseases, Vol. 63, No. 7, 01.10.2016, p. 944-948.

Research output: Contribution to journalReview article

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