Differential 18F-FDG and 18F-Fluciclovine Uptake Pattern in a Patient with Poorly Differentiated Adenocarcinoma of the Lung and Prostate Cancer Biochemical Recurrence

Nghi C. Nguyen, Ashok Muthukrishnan, James M. Mountz

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A 72-year-old man with a history of T1cN0M0 prostate adenocarcinoma and rising prostate-specific antigen underwent a fluciclovine PET/CT scan that showed high uptake in several para-aortic nodes, suspicious for prostate cancer. A right upper lobe single pulmonary nodule (SPN), demonstrated only mild uptake, which raised the suspicion for a lung primary. Subsequent FDG PET/CT showed high uptake in the SPN, revealing poorly differentiated adenocarcinoma at biopsy, but with no abnormal uptake in the para-aortic nodes. This case highlights the complementary potential of fluciclovine and FDG PET in patients with a history of prostate cancer biochemical recurrence and SPN.

Original languageEnglish (US)
Pages (from-to)E63-E64
JournalClinical nuclear medicine
Volume45
Issue number1
DOIs
StatePublished - Jan 1 2020
Externally publishedYes

Keywords

  • F-fluciclovine
  • FDG PET
  • fluciclovine PET
  • lung adenocarcinoma
  • PET/CT
  • prostate adenocarcinoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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