Disseminated adenoviral infection presenting as acute pancreatitis

Theodore H. Niemann, Michael E. Trigg, Naomi Winick, George D. Penick

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Adenoviruses are gradually being recognized as a significant source of morbidity and mortality in the immunocompromised patient population. We report a bone marrow transplant patient who developed severe abdominal pain accompanied by marked elevations in serum pancreatic and hepatic enzyme levels. She died shortly thereafter. Autopsy revealed hemorrhagic pancreatitis and fulminant hepatic necrosis. Both the pancreas and liver contained intranuclear inclusions consistent with adenovirus; electron microscopy confirmed that there were, indeed, adenoviral particles. This report of adenoviral pancreatitis emphasizes the diversity of manifestations seen with adenoviral infection.

Original languageEnglish (US)
Pages (from-to)1145-1148
Number of pages4
JournalHuman Pathology
Volume24
Issue number10
DOIs
StatePublished - Oct 1993

Keywords

  • adenovirus
  • bone marrow transplant
  • hepatitis
  • pancreatitis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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