Disseminated adenoviral infection presenting as acute pancreatitis

Theodore H. Niemann, Michael E. Trigg, Naomi Winick, George D. Penick

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Adenoviruses are gradually being recognized as a significant source of morbidity and mortality in the immunocompromised patient population. We report a bone marrow transplant patient who developed severe abdominal pain accompanied by marked elevations in serum pancreatic and hepatic enzyme levels. She died shortly thereafter. Autopsy revealed hemorrhagic pancreatitis and fulminant hepatic necrosis. Both the pancreas and liver contained intranuclear inclusions consistent with adenovirus; electron microscopy confirmed that there were, indeed, adenoviral particles. This report of adenoviral pancreatitis emphasizes the diversity of manifestations seen with adenoviral infection.

Original languageEnglish (US)
Pages (from-to)1145-1148
Number of pages4
JournalHuman Pathology
Volume24
Issue number10
DOIs
StatePublished - 1993

Fingerprint

Pancreatitis
Adenoviridae
Liver
Infection
Intranuclear Inclusion Bodies
Immunocompromised Host
Abdominal Pain
Pancreas
Autopsy
Electron Microscopy
Necrosis
Bone Marrow
Morbidity
Transplants
Mortality
Enzymes
Serum
Population

Keywords

  • adenovirus
  • bone marrow transplant
  • hepatitis
  • pancreatitis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Disseminated adenoviral infection presenting as acute pancreatitis. / Niemann, Theodore H.; Trigg, Michael E.; Winick, Naomi; Penick, George D.

In: Human Pathology, Vol. 24, No. 10, 1993, p. 1145-1148.

Research output: Contribution to journalArticle

Niemann, Theodore H. ; Trigg, Michael E. ; Winick, Naomi ; Penick, George D. / Disseminated adenoviral infection presenting as acute pancreatitis. In: Human Pathology. 1993 ; Vol. 24, No. 10. pp. 1145-1148.
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