Abstract
In this issue, Fan et al. (2016) show that oncogenic tyrosine kinases can promote glycolysis by phosphorylating and stabilizing the tetrameric form of mitochondrial acetyl-coA acetyltransferase 1 (ACAT1). The authors further identify a small molecule ACAT1 inhibitor that displays anti-cancer effects.
Original language | English (US) |
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Pages (from-to) | 856-857 |
Number of pages | 2 |
Journal | Molecular cell |
Volume | 64 |
Issue number | 5 |
DOIs | |
State | Published - Dec 1 2016 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology