Dynamic Contrast-Enhanced MR Imaging in the Evaluation of Patients with Prostate Cancer

Colm J. McMahon, B. Nicolas Bloch, Robert E. Lenkinski, Neil M. Rofsky

Research output: Contribution to journalReview article

37 Scopus citations

Abstract

Prostate cancer is a common tumor among men, with increasing diagnosis at an earlier stage and a lower volume of disease because of screening with prostate-specific antigen (PSA). The need for imaging of the prostate stems from a desire to optimize treatment strategy on a patient and tumor-specific level. The major goals of prostate imaging are (1) staging of known cancer, (2) determination of tumor aggressiveness, (3) diagnosis of cancer in patients who have elevated PSA but a negative biopsy, (4) treatment planning, and (5) the evaluation of therapy response. This article concentrates on the role of dynamic contrast-enhanced MR imaging in the evaluation of patients who have prostate cancer and how it might be used to help achieve the above goals. Various dynamic contrast enhancement approaches (quantitative/semiquantitative/qualitative, high temporal versus high spatial resolution) are summarized with reference to the relevant strengths and compromises of each approach.

Original languageEnglish (US)
Pages (from-to)363-383
Number of pages21
JournalMagnetic resonance imaging clinics of North America
Volume17
Issue number2
DOIs
StatePublished - May 1 2009

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Keywords

  • Contrast media
  • Gadolinium-DTPA
  • Kinetics
  • MR imaging
  • Neoplasm staging
  • Prostatic neoplasm

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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