Dynamic Jaws and Dynamic Couch in Helical Tomotherapy

Florian Sterzing, Matthias Uhl, Henrik Hauswald, Kai Schubert, Gabriele Sroka-Perez, Yu Chen, Weiguo Lu, Rock Mackie, Jürgen Debus, Klaus Herfarth, Gustavo Oliveira

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Purpose: To investigate the next generation of helical tomotherapy delivery with dynamic jaw and dynamic couch movements. Methods and Materials: The new technique of dynamic jaw and dynamic couch movements is described, and a comparative planning study is performed. Ten nasopharyngeal cancer patients with skull base infiltration were chosen for this comparison of longitudinal dose profiles using regular tomotherapy delivery, running-start-stop treatment, and dynamic jaw and dynamic couch delivery. A multifocal simultaneous integrated boost concept was used (70.4Gy to the primary tumor and involved lymph nodes; 57.4Gy to the bilateral cervical lymphatic drainage pathways, 32 fractions). Target coverage, conformity, homogeneity, sparing of organs at risk, integral dose, and radiation delivery time were evaluated. Results: Mean parotid dose for all different deliveries was between 24.8 and 26.1Gy, without significant differences. The mean integral dose was lowered by 6.3% by using the dynamic technique, in comparison with a 2.5-cm-field width for regular delivery and 16.7% with 5-cm-field width for regular delivery. Dynamic jaw and couch movements reduced the calculated radiation time by 66% of the time required with regular 2.5-cm-field width delivery (199 sec vs. 595 sec, p < 0.001). Conclusions: The current delivery mode of helical tomotherapy produces dose distributions with conformal avoidance of parotid glands, brain stem, and spinal cord. The new technology with dynamic jaw and couch movements improves the plan quality by reducing the dose penumbra and thereby reducing the integral dose. In addition, radiation time is reduced by 66% of the regular delivery time.

Original languageEnglish (US)
Pages (from-to)1266-1273
Number of pages8
JournalInternational Journal of Radiation Oncology Biology Physics
Volume76
Issue number4
DOIs
StatePublished - Mar 15 2010

Keywords

  • Dynamic couch
  • Dynamic jaws
  • Helical tomotherapy
  • Longitudinal dose profile
  • Nasopharyngeal cancer

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

Fingerprint Dive into the research topics of 'Dynamic Jaws and Dynamic Couch in Helical Tomotherapy'. Together they form a unique fingerprint.

Cite this