Dysmorphic villi mimicking partial mole in a case with del(18)(q21)

Dinesh Rakheja, Kathleen S Wilson, Beverly B. Rogers

Research output: Contribution to journalArticle

Abstract

In this article, we report the histopathologic findings in a placenta from an early second trimester abortion. The placental villi showed prominent scalloping with many intravillous trophoblastic pseudoinclusions and mild trophoblastic hyperplasia, mimicking the morphology of partial hydatidiform mole. The placental karyotype was 46,XY,del(18)(q21). These histopathologic changes have been previously described in numerical chromosomal aberrations like triploidy, tetraploidy, and trisomies, but not in structural chromosomal abnormalities.

Original languageEnglish (US)
Pages (from-to)546-548
Number of pages3
JournalPediatric and Developmental Pathology
Volume7
Issue number5
DOIs
StatePublished - Nov 1 2004

Keywords

  • Chromosomal deletion
  • Dysmorphic villi
  • Partial hydatidiform mole

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

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