Ectopic atypical parathyroid lipoadenoma: A rare cause of severe primary hyperparathyroidism

Vivienne Yoon, Kristina Treat, Naim M. Maalouf

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Parathyroid lipoadenomas are a rare and benign variant of parathyroid adenomas that are defined morphologically by an abundance of fat cells. They may be functional with secretion of parathyroid hormone or nonfunctional. We present a case of a parathyroid lipoadenoma in a patient presenting with clinical manifestations of severe primary hyperparathyroidism. Unusual features in this case included the ectopic location of the lipoadenoma in the mediastinum, the significant size of 6.6 × 3.4 cm, and weight of 30.1 g. In addition to the large size of this generally benign type of parathyroid neoplasm, histologic findings included focal band-forming fibrosis compatible with the diagnosis of an atypical parathyroid adenoma. In conclusion, this case illustrates a difficult case of an ectopic functioning parathyroid lipoadenoma with chronic sequelae due to severe hyperparathyroidism.

Original languageEnglish (US)
Pages (from-to)595-600
Number of pages6
JournalJournal of Bone and Mineral Metabolism
Volume31
Issue number5
DOIs
Publication statusPublished - 2013

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Keywords

  • Atypical parathyroid adenoma
  • Parathyroid lipoadenoma

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine

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