EEG-triggered echo-planar functional MRI in epilepsy

S. Warach, J. R. Ives, G. Schlaug, M. R. Patel, D. G. Darby, V. Thangaraj, R. R. Edelman, D. L. Schomer

Research output: Contribution to journalArticle

217 Citations (Scopus)

Abstract

We investigated whether: (1) EEG recordings could be successfully performed in an MRI imager, (2) subclinical epileptic discharges could be used to trigger ultrafast functional MRI images, (3) artifact-free functional MRI images could be obtained while the patient was having the EEG monitored, and (4) the functional MRI images so obtained would show focal signal increases in relation to epileptic discharges. We report our results in two patients who showed focally higher signal intensity, reflective of increased local blood flow, in ultrafast functional MRI timed to epileptic discharges recorded while the patients were in the imager and compared with images not associated with discharges. One patient showed a focal increase despite a clinical and EEG history of generalized discharges. This approach may have the potential to identify brain regions activated during brief focal epileptic discharges.

Original languageEnglish (US)
Pages (from-to)89-93
Number of pages5
JournalNeurology
Volume47
Issue number1
StatePublished - Jul 1996

Fingerprint

Electroencephalography
Epilepsy
Magnetic Resonance Imaging
Artifacts
Brain

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Warach, S., Ives, J. R., Schlaug, G., Patel, M. R., Darby, D. G., Thangaraj, V., ... Schomer, D. L. (1996). EEG-triggered echo-planar functional MRI in epilepsy. Neurology, 47(1), 89-93.

EEG-triggered echo-planar functional MRI in epilepsy. / Warach, S.; Ives, J. R.; Schlaug, G.; Patel, M. R.; Darby, D. G.; Thangaraj, V.; Edelman, R. R.; Schomer, D. L.

In: Neurology, Vol. 47, No. 1, 07.1996, p. 89-93.

Research output: Contribution to journalArticle

Warach, S, Ives, JR, Schlaug, G, Patel, MR, Darby, DG, Thangaraj, V, Edelman, RR & Schomer, DL 1996, 'EEG-triggered echo-planar functional MRI in epilepsy', Neurology, vol. 47, no. 1, pp. 89-93.
Warach S, Ives JR, Schlaug G, Patel MR, Darby DG, Thangaraj V et al. EEG-triggered echo-planar functional MRI in epilepsy. Neurology. 1996 Jul;47(1):89-93.
Warach, S. ; Ives, J. R. ; Schlaug, G. ; Patel, M. R. ; Darby, D. G. ; Thangaraj, V. ; Edelman, R. R. ; Schomer, D. L. / EEG-triggered echo-planar functional MRI in epilepsy. In: Neurology. 1996 ; Vol. 47, No. 1. pp. 89-93.
@article{b9f06627a4114f5b9b1a188c4e51ae90,
title = "EEG-triggered echo-planar functional MRI in epilepsy",
abstract = "We investigated whether: (1) EEG recordings could be successfully performed in an MRI imager, (2) subclinical epileptic discharges could be used to trigger ultrafast functional MRI images, (3) artifact-free functional MRI images could be obtained while the patient was having the EEG monitored, and (4) the functional MRI images so obtained would show focal signal increases in relation to epileptic discharges. We report our results in two patients who showed focally higher signal intensity, reflective of increased local blood flow, in ultrafast functional MRI timed to epileptic discharges recorded while the patients were in the imager and compared with images not associated with discharges. One patient showed a focal increase despite a clinical and EEG history of generalized discharges. This approach may have the potential to identify brain regions activated during brief focal epileptic discharges.",
author = "S. Warach and Ives, {J. R.} and G. Schlaug and Patel, {M. R.} and Darby, {D. G.} and V. Thangaraj and Edelman, {R. R.} and Schomer, {D. L.}",
year = "1996",
month = "7",
language = "English (US)",
volume = "47",
pages = "89--93",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - EEG-triggered echo-planar functional MRI in epilepsy

AU - Warach, S.

AU - Ives, J. R.

AU - Schlaug, G.

AU - Patel, M. R.

AU - Darby, D. G.

AU - Thangaraj, V.

AU - Edelman, R. R.

AU - Schomer, D. L.

PY - 1996/7

Y1 - 1996/7

N2 - We investigated whether: (1) EEG recordings could be successfully performed in an MRI imager, (2) subclinical epileptic discharges could be used to trigger ultrafast functional MRI images, (3) artifact-free functional MRI images could be obtained while the patient was having the EEG monitored, and (4) the functional MRI images so obtained would show focal signal increases in relation to epileptic discharges. We report our results in two patients who showed focally higher signal intensity, reflective of increased local blood flow, in ultrafast functional MRI timed to epileptic discharges recorded while the patients were in the imager and compared with images not associated with discharges. One patient showed a focal increase despite a clinical and EEG history of generalized discharges. This approach may have the potential to identify brain regions activated during brief focal epileptic discharges.

AB - We investigated whether: (1) EEG recordings could be successfully performed in an MRI imager, (2) subclinical epileptic discharges could be used to trigger ultrafast functional MRI images, (3) artifact-free functional MRI images could be obtained while the patient was having the EEG monitored, and (4) the functional MRI images so obtained would show focal signal increases in relation to epileptic discharges. We report our results in two patients who showed focally higher signal intensity, reflective of increased local blood flow, in ultrafast functional MRI timed to epileptic discharges recorded while the patients were in the imager and compared with images not associated with discharges. One patient showed a focal increase despite a clinical and EEG history of generalized discharges. This approach may have the potential to identify brain regions activated during brief focal epileptic discharges.

UR - http://www.scopus.com/inward/record.url?scp=0030015933&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030015933&partnerID=8YFLogxK

M3 - Article

C2 - 8710131

AN - SCOPUS:0030015933

VL - 47

SP - 89

EP - 93

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 1

ER -