Effect of acquisition parameters on the accuracy of velocity encoded cine magnetic resonance imaging blood flow measurements

Gerald Greil, Tal Geva, Stephan E. Maier, Andrew J. Powell

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

Purpose: To investigate the effect of acquisition parameters on the accuracy of 2D velocity encoded cine magnetic resonance imaging (VEC MRI) flow measurements. Materials and Methods: Using a pulsatile flow phantom, through-plane flow measurements were performed on a flexible vessel made of polyvinyl alcohol cryogel (PVA), a material that mimics the MR signal and biomechanical properties of aortic tissue. Results: Repeated VEC MRI flow measurements (N = 20) under baseline conditions yielded an error of 0.8 ± 1.5%. Slice thickness, angle between flow and velocity encoding directions, spatial resolution, velocity encoding range, and radio frequency (RF) flip angles were varied over a clinically relevant range. Spatial resolution had the greatest impact on accuracy, with a 9% overestimation of flow at 16 pixels per vessel cross-section. Conclusion: VEC MRI proved to be an accurate and reproducible technique for pulsatile flow measurements over the range of acquisition parameters examined as long as sufficient spatial resolution was prescribed.

Original languageEnglish (US)
Pages (from-to)47-54
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Volume15
Issue number1
DOIs
StatePublished - Jan 5 2002

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Keywords

  • Blood flow
  • MR phase velocity imaging
  • Magnetic resonance imaging
  • Polyvinyl alcohol cryogel
  • Pulsatile blood flow
  • Velocity encoded cine MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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