Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure

Raichel Alex, Suvidha Manchikatla, Karthik Machiraju, Essam Altuwaijri, Donald E. Watenpaugh, Rong Zhang, Khosrow Behbehani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

13 Scopus citations

Abstract

Obstructive Sleep Apnea (OSA), defined by shallow breaths or complete cessation of breathing for more than 10s, is a significant contributing factor for the developments of hypertension, myocardial infarction, stroke and neuropsychological impairments. In this study, we have investigated the relation between apnea duration and apnea induced variations in cerebral blood flow velocity (CBFV) concomitant with blood pressure changes in 9 sleep apnea subjects (8 male and 1 female; Age: 46.0±11.6 years; BMI: 34.5±7.8 kg/m<sup>2</sup>; AHI: 81.6±41). As apnea duration increased from 10s to greater than 30s, the mean percentage rise in CBFV increased from 22% to 42% for amplitude and 22% to 33% for area respectively. For blood pressure, the values increased from 14% to 26% for amplitude and 14% to 23% for area respectively. The results suggest that the apnea duration has a measurable effect on the degree of rise in both cerebral blood flow velocity and arterial blood pressure during apnea episodes (p=0.0002).

Original languageEnglish (US)
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages270-273
Number of pages4
ISBN (Print)9781424479290
DOIs
StatePublished - Nov 2 2014
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: Aug 26 2014Aug 30 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period8/26/148/30/14

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering

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