Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure

Raichel Alex; Suvidha Manchikatla; Karthik Machiraju; Essam Altuwaijri; Donald E. Watenpaugh; Rong Zhang; Khosrow Behbehani

doi:10.1109/EMBC.2014.6943581

Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure

Raichel Alex, Suvidha Manchikatla, Karthik Machiraju, Essam Altuwaijri, Donald E. Watenpaugh, Rong Zhang, Khosrow Behbehani

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

15 Scopus citations

Abstract

Obstructive Sleep Apnea (OSA), defined by shallow breaths or complete cessation of breathing for more than 10s, is a significant contributing factor for the developments of hypertension, myocardial infarction, stroke and neuropsychological impairments. In this study, we have investigated the relation between apnea duration and apnea induced variations in cerebral blood flow velocity (CBFV) concomitant with blood pressure changes in 9 sleep apnea subjects (8 male and 1 female; Age: 46.0±11.6 years; BMI: 34.5±7.8 kg/m<sup>2</sup>; AHI: 81.6±41). As apnea duration increased from 10s to greater than 30s, the mean percentage rise in CBFV increased from 22% to 42% for amplitude and 22% to 33% for area respectively. For blood pressure, the values increased from 14% to 26% for amplitude and 14% to 23% for area respectively. The results suggest that the apnea duration has a measurable effect on the degree of rise in both cerebral blood flow velocity and arterial blood pressure during apnea episodes (p=0.0002).

Original language	English (US)
Title of host publication	2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	270-273
Number of pages	4
ISBN (Print)	9781424479290
DOIs	https://doi.org/10.1109/EMBC.2014.6943581
State	Published - Nov 2 2014
Event	2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States Duration: Aug 26 2014 → Aug 30 2014

Other

Other	2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
Country/Territory	United States
City	Chicago
Period	8/26/14 → 8/30/14

ASJC Scopus subject areas

Health Informatics
Computer Science Applications
Biomedical Engineering

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10.1109/EMBC.2014.6943581

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Alex, R., Manchikatla, S., Machiraju, K., Altuwaijri, E., Watenpaugh, D. E., Zhang, R., & Behbehani, K. (2014). Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 (pp. 270-273). [6943581] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2014.6943581

Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure. / Alex, Raichel; Manchikatla, Suvidha; Machiraju, Karthik; Altuwaijri, Essam; Watenpaugh, Donald E.; Zhang, Rong; Behbehani, Khosrow.

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 270-273 6943581.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Alex, R, Manchikatla, S, Machiraju, K, Altuwaijri, E, Watenpaugh, DE, Zhang, R & Behbehani, K 2014, Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure. in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014., 6943581, Institute of Electrical and Electronics Engineers Inc., pp. 270-273, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Chicago, United States, 8/26/14. https://doi.org/10.1109/EMBC.2014.6943581

Alex R, Manchikatla S, Machiraju K, Altuwaijri E, Watenpaugh DE, Zhang R et al. Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 270-273. 6943581 https://doi.org/10.1109/EMBC.2014.6943581

Alex, Raichel ; Manchikatla, Suvidha ; Machiraju, Karthik ; Altuwaijri, Essam ; Watenpaugh, Donald E. ; Zhang, Rong ; Behbehani, Khosrow. / Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 270-273

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Effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure

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