Effect of increasing central venous pressure during passive heating on skin blood flow

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Whole body heating in humans increases skin blood flow (SkBF) and decreases central venous pressure (CVP). This study sought to identify whether elevations in SkBF are augmented during passive heating if CVP is increased during the heat stress. Seven subjects were exposed to passive heating. Once SkBF was substantially elevated, 15 ml/kg warm saline were rapidly infused intravenously. Whole body heating significantly increased cutaneous vascular conductance and decreased CVP from 7.7 ± 0.6 to 4.9 ± 0.5 mmHg (P < 0.05). Saline infusion returned CVP to pre-heat-stress pressures (7.9 ± 0.6 mmHg; P > 0.05) and significantly increased cutaneous vascular conductance relative to the period before saline administration. Moreover, saline infusion did not alter mean arterial pressure, pulse pressure, or esophageal temperature (all P > 0.05). To serve as a volume control, 15 ml/kg saline were rapidly infused intravenously in normothermic subjects. Saline infusion increased CVP (P < 0.05) without affecting mean arterial pressure, pulse pressure, or cutaneous vascular conductance (all P > 0.05). These data suggest that cardiopulmonary baroreceptor unloading during passive heating may attenuate the elevation in SkBF in humans, whereas loading cardiopulmonary baroreceptors in normothermia has no effect on SkBF.

Original languageEnglish (US)
Pages (from-to)605-610
Number of pages6
JournalJournal of Applied Physiology
Volume86
Issue number2
StatePublished - Feb 1999

Fingerprint

Central Venous Pressure
Heating
Skin
Pressoreceptors
Blood Vessels
Arterial Pressure
Hot Temperature
Blood Pressure
Temperature

Keywords

  • Baroreflex
  • Cardiopulmonary baroreceptors
  • Cutaneous vascular conductance
  • Human
  • Peripheral circulation
  • Temperature regulation

ASJC Scopus subject areas

  • Physiology
  • Endocrinology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Effect of increasing central venous pressure during passive heating on skin blood flow. / Crandall, C. G.; Levine, B. D.; Etzel, R. A.

In: Journal of Applied Physiology, Vol. 86, No. 2, 02.1999, p. 605-610.

Research output: Contribution to journalArticle

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