Effect of perfusion on exercised muscle

MR imaging evaluation.

B. T. Archer, J. L. Fleckenstein, L. A. Bertocci, Ronald G Haller, B. Barker, R. W. Parkey, Ronald M Peshock

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

An ischemic clamp model of exercise was used to evaluate the potential role of blood flow in mediating changes in the magnetic resonance imaging appearance of skeletal muscle. Proton relaxation times of muscle were serially estimated in 10 healthy subjects (a) before exercise, (b) after exercise in the presence of vascular occlusion (VO1), (c) during vascular reocclusion after 1 minute of reperfusion (VO2), and (d) after reinstitution of continuous flow. T1 and T2 of active muscles were increased during VO1. During VO2, there were additional increases in relaxation times of active muscles. Reinstitution of continuous flow was associated with a continuous decrease in the T2 of exercised muscle. Hence, blood flow was not required for increases in T1 and T2 with exercise. Additional relaxation time increases occurred after a brief period of reperfusion; however, continuous flow was associated with a decrease in T2.

Original languageEnglish (US)
Pages (from-to)407-413
Number of pages7
JournalJournal of magnetic resonance imaging : JMRI
Volume2
Issue number4
StatePublished - Jul 1992

Fingerprint

Perfusion
Exercise
Muscles
Reperfusion
Blood Vessels
Muscle Relaxation
Protons
Healthy Volunteers
Skeletal Muscle
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Archer, B. T., Fleckenstein, J. L., Bertocci, L. A., Haller, R. G., Barker, B., Parkey, R. W., & Peshock, R. M. (1992). Effect of perfusion on exercised muscle: MR imaging evaluation. Journal of magnetic resonance imaging : JMRI, 2(4), 407-413.

Effect of perfusion on exercised muscle : MR imaging evaluation. / Archer, B. T.; Fleckenstein, J. L.; Bertocci, L. A.; Haller, Ronald G; Barker, B.; Parkey, R. W.; Peshock, Ronald M.

In: Journal of magnetic resonance imaging : JMRI, Vol. 2, No. 4, 07.1992, p. 407-413.

Research output: Contribution to journalArticle

Archer, BT, Fleckenstein, JL, Bertocci, LA, Haller, RG, Barker, B, Parkey, RW & Peshock, RM 1992, 'Effect of perfusion on exercised muscle: MR imaging evaluation.', Journal of magnetic resonance imaging : JMRI, vol. 2, no. 4, pp. 407-413.
Archer BT, Fleckenstein JL, Bertocci LA, Haller RG, Barker B, Parkey RW et al. Effect of perfusion on exercised muscle: MR imaging evaluation. Journal of magnetic resonance imaging : JMRI. 1992 Jul;2(4):407-413.
Archer, B. T. ; Fleckenstein, J. L. ; Bertocci, L. A. ; Haller, Ronald G ; Barker, B. ; Parkey, R. W. ; Peshock, Ronald M. / Effect of perfusion on exercised muscle : MR imaging evaluation. In: Journal of magnetic resonance imaging : JMRI. 1992 ; Vol. 2, No. 4. pp. 407-413.
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